Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2527545..2527816 Replicon chromosome
Accession NZ_CP086338
Organism Escherichia coli strain EJN001

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2527583..2527686 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2527545..2527816 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5N09_RS12180 2524702..2526141 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
C5N09_RS12185 2526259..2526495 + 237 WP_001295499.1 YebV family protein -
C5N09_RS12190 2526600..2526791 + 192 WP_000457842.1 YebW family protein -
C5N09_RS12195 2526792..2527448 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2527545..2527816 + 272 - - Antitoxin
- 2527583..2527686 - 104 - - Toxin
C5N09_RS12200 2527844..2528185 - 342 WP_000976476.1 YebY family protein -
C5N09_RS12205 2528198..2529070 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
C5N09_RS12210 2529074..2529448 - 375 WP_000168747.1 CopC domain-containing protein YobA -
C5N09_RS12215 2529587..2529817 + 231 WP_000916763.1 DNA polymerase III subunit theta -
C5N09_RS12220 2529919..2530575 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
C5N09_RS12225 2530599..2531261 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T223037 NZ_CP086338:c2527686-2527583 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT223037 NZ_CP086338:2527545-2527816 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References