Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 3525681..3526902 | Replicon | chromosome |
| Accession | NC_009656 | ||
| Organism | Pseudomonas aeruginosa PA7 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | A0A3S0L3G0 |
| Locus tag | PSPA7_RS16175 | Protein ID | WP_003153547.1 |
| Coordinates | 3526324..3526902 (+) | Length | 193 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | PSPA7_RS16170 | Protein ID | WP_003153549.1 |
| Coordinates | 3525681..3526235 (+) | Length | 185 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PSPA7_RS16145 | 3521250..3521801 | + | 552 | WP_012076111.1 | XRE family transcriptional regulator | - |
| PSPA7_RS16150 | 3521798..3522196 | - | 399 | WP_012076112.1 | NADH-quinone oxidoreductase subunit A | - |
| PSPA7_RS16155 | 3522209..3522532 | - | 324 | WP_012076113.1 | quaternary ammonium compound efflux SMR transporter SugE | - |
| PSPA7_RS16160 | 3522862..3523323 | + | 462 | WP_012076114.1 | (2Fe-2S)-binding protein | - |
| PSPA7_RS16165 | 3523328..3525523 | + | 2196 | WP_012076115.1 | xanthine dehydrogenase family protein molybdopterin-binding subunit | - |
| PSPA7_RS16170 | 3525681..3526235 | + | 555 | WP_003153549.1 | helix-turn-helix domain-containing protein | Antitoxin |
| PSPA7_RS16175 | 3526324..3526902 | + | 579 | WP_003153547.1 | HD domain-containing protein | Toxin |
| PSPA7_RS16180 | 3527011..3528198 | - | 1188 | WP_012076116.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| PSPA7_RS16185 | 3528188..3530359 | - | 2172 | WP_041025362.1 | type I secretion system permease/ATPase | - |
| PSPA7_RS16190 | 3530349..3531626 | - | 1278 | WP_003153546.1 | TolC family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 193 a.a. Molecular weight: 21852.75 Da Isoelectric Point: 5.6237
>T22301 WP_003153547.1 NC_009656:3526324-3526902 [Pseudomonas aeruginosa PA7]
MSLELLKNRLDFLREAERLKDVLRSAHTSSGRPESTAEHSWRLCLMALAFEDQLAGLDLGKVLRMCVVHDLGEAIHGDIP
AVEQAAHPDKGEQERADLLQLTRHLDAPLRERLLALWDEYERGESAEALAVKALDKLETLLQHTQGDNPADFDYAFNLDY
GRRYTDRAPLFKALRELLDAKTRQRLAARRDA
MSLELLKNRLDFLREAERLKDVLRSAHTSSGRPESTAEHSWRLCLMALAFEDQLAGLDLGKVLRMCVVHDLGEAIHGDIP
AVEQAAHPDKGEQERADLLQLTRHLDAPLRERLLALWDEYERGESAEALAVKALDKLETLLQHTQGDNPADFDYAFNLDY
GRRYTDRAPLFKALRELLDAKTRQRLAARRDA
Download Length: 579 bp
>T22301 NC_009656:3526324-3526902 [Pseudomonas aeruginosa PA7]
ATGTCCCTCGAACTGCTGAAGAACCGCCTCGACTTCCTCCGCGAAGCCGAACGCCTGAAAGATGTCCTGCGCTCCGCGCA
TACGTCTTCCGGTCGCCCGGAAAGCACCGCCGAACACAGTTGGCGGCTGTGCCTGATGGCGCTGGCCTTCGAGGATCAAC
TGGCCGGCCTGGACCTCGGCAAGGTCCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCA
GCCGTCGAGCAGGCCGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGTTGACTCGTCACCTCGACGC
GCCGCTGCGCGAACGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGGCCCTGCGCGAGCTACTCGACGCCAAGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG
ATGTCCCTCGAACTGCTGAAGAACCGCCTCGACTTCCTCCGCGAAGCCGAACGCCTGAAAGATGTCCTGCGCTCCGCGCA
TACGTCTTCCGGTCGCCCGGAAAGCACCGCCGAACACAGTTGGCGGCTGTGCCTGATGGCGCTGGCCTTCGAGGATCAAC
TGGCCGGCCTGGACCTCGGCAAGGTCCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCA
GCCGTCGAGCAGGCCGCGCACCCGGACAAGGGCGAACAGGAACGCGCCGACCTGTTGCAGTTGACTCGTCACCTCGACGC
GCCGCTGCGCGAACGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGGCCCTGCGCGAGCTACTCGACGCCAAGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG
Antitoxin
Download Length: 185 a.a. Molecular weight: 20423.53 Da Isoelectric Point: 8.9546
>AT22301 WP_003153549.1 NC_009656:3525681-3526235 [Pseudomonas aeruginosa PA7]
MTEPLPSSSLGPALRRWRLLHRVKQAHAAELFGVAQSTISRWESGAQALRAEERTRLETLLGARLETAADRALARLVDGS
PQPMHLICDLTHRLLACSPARATQFAVPLGDLLGRSLWPYCSEEILRQEAALEDLGWRELLAPPALEFASGTNASTIVPI
RRSRCRWTRLTLSDGRAVRLVETL
MTEPLPSSSLGPALRRWRLLHRVKQAHAAELFGVAQSTISRWESGAQALRAEERTRLETLLGARLETAADRALARLVDGS
PQPMHLICDLTHRLLACSPARATQFAVPLGDLLGRSLWPYCSEEILRQEAALEDLGWRELLAPPALEFASGTNASTIVPI
RRSRCRWTRLTLSDGRAVRLVETL
Download Length: 555 bp
>AT22301 NC_009656:3525681-3526235 [Pseudomonas aeruginosa PA7]
ATGACCGAGCCTCTTCCTTCTTCGTCCCTGGGCCCCGCCCTGCGCCGCTGGCGCCTGCTGCACCGGGTCAAGCAGGCGCA
CGCCGCCGAGCTGTTCGGCGTGGCCCAGTCGACCATCTCGCGCTGGGAGTCCGGCGCCCAGGCACTGCGGGCGGAGGAAC
GGACACGCCTGGAAACCCTCCTCGGCGCCCGCCTGGAGACCGCCGCCGACCGGGCGCTGGCCCGCCTGGTCGATGGCAGC
CCGCAGCCGATGCATCTGATCTGCGACCTCACCCACCGCCTGCTGGCCTGCTCGCCGGCGCGCGCCACGCAATTCGCCGT
CCCCCTCGGCGACCTGCTCGGCCGTTCGCTGTGGCCGTATTGCAGCGAGGAGATCCTCCGCCAGGAAGCCGCCCTCGAGG
ACCTCGGCTGGCGCGAGCTGCTGGCGCCGCCGGCGCTGGAGTTCGCCAGCGGAACGAACGCCTCGACCATCGTGCCGATC
CGGCGCAGCCGCTGCCGCTGGACCCGCCTGACGCTCTCCGACGGCCGCGCGGTGCGGCTGGTGGAAACCCTCTGA
ATGACCGAGCCTCTTCCTTCTTCGTCCCTGGGCCCCGCCCTGCGCCGCTGGCGCCTGCTGCACCGGGTCAAGCAGGCGCA
CGCCGCCGAGCTGTTCGGCGTGGCCCAGTCGACCATCTCGCGCTGGGAGTCCGGCGCCCAGGCACTGCGGGCGGAGGAAC
GGACACGCCTGGAAACCCTCCTCGGCGCCCGCCTGGAGACCGCCGCCGACCGGGCGCTGGCCCGCCTGGTCGATGGCAGC
CCGCAGCCGATGCATCTGATCTGCGACCTCACCCACCGCCTGCTGGCCTGCTCGCCGGCGCGCGCCACGCAATTCGCCGT
CCCCCTCGGCGACCTGCTCGGCCGTTCGCTGTGGCCGTATTGCAGCGAGGAGATCCTCCGCCAGGAAGCCGCCCTCGAGG
ACCTCGGCTGGCGCGAGCTGCTGGCGCCGCCGGCGCTGGAGTTCGCCAGCGGAACGAACGCCTCGACCATCGTGCCGATC
CGGCGCAGCCGCTGCCGCTGGACCCGCCTGACGCTCTCCGACGGCCGCGCGGTGCGGCTGGTGGAAACCCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|