222976

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4553694..4554079 Replicon chromosome
Accession NZ_CP086333
Organism Xanthomonas translucens pv. arrhenatheri strain LMG 727

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag KM317_RS19185 Protein ID WP_003469322.1
Coordinates 4553694..4553828 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A0K2ZNU2
Locus tag KM317_RS19190 Protein ID WP_009574163.1
Coordinates 4553927..4554079 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KM317_RS19165 (KM317_19160) 4549742..4550665 - 924 WP_053834664.1 MBL fold metallo-hydrolase -
KM317_RS19170 (KM317_19165) 4550944..4552254 - 1311 WP_053834663.1 tryptophan--tRNA ligase -
KM317_RS19175 (KM317_19170) 4552365..4553207 + 843 WP_053834662.1 hypothetical protein -
KM317_RS19180 (KM317_19175) 4553278..4553493 - 216 WP_053834661.1 CsbD family protein -
KM317_RS19185 (KM317_19180) 4553694..4553828 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
KM317_RS19190 (KM317_19185) 4553927..4554079 - 153 WP_009574163.1 entericidin A/B family lipoprotein Antitoxin
KM317_RS19195 (KM317_19190) 4554224..4555147 - 924 WP_053834660.1 arginase -
KM317_RS19205 (KM317_19200) 4555575..4556411 - 837 WP_053834659.1 SPOR domain-containing protein -
KM317_RS19210 (KM317_19205) 4556421..4557161 - 741 WP_053834658.1 type III pantothenate kinase -
KM317_RS19215 (KM317_19210) 4557158..4558129 - 972 WP_053834657.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
KM317_RS19220 (KM317_19215) 4558291..4558566 + 276 WP_186008637.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T222976 WP_003469322.1 NZ_CP086333:c4553828-4553694 [Xanthomonas translucens pv. arrhenatheri]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T222976 NZ_CP118233:c4988986-4988561 [Micromonospora chalcea]
GTGAAGCTGGCCGACTACCTGATCGACACCAGCGCCCTCGTCCGGCTCCTGCGTGATCCCGACGTGCTGGCGCGCTGGGA
ACAGCAGGTGACAGCGGGTCTGCTCGCCGTGTGCCCGCTGGTCGAGCTGGAATTCCTCTACACCGCCCGGTCGGTCGCCG
ACCGGACGCGCCTGACCGAGCAGCTCCGGGCCGCCTTCGGCTGGGTGGTCATGCCGGACCGGATCTACGAACGCGCCGCC
GAGATCCAGGGCGAGCTGACCGTGCGGGGGACGCACCGCTCGGCGGGCGCGGTCGACCTGCTCATCGCCGCCACCGCCGA
GTACCACGGTCTCTCGCTGCTGCACTACGACCGGGACTTCGACCAGGTCGGCGCCGTCACCGGCCAGCCGATGCGCTGGC
TGACCCGACCCGGCTCGATCAAATAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5393.44 Da        Isoelectric Point: 8.1210

>AT222976 WP_009574163.1 NZ_CP086333:c4554079-4553927 [Xanthomonas translucens pv. arrhenatheri]
MKRLFTLMMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVENKADDCKDGKC

Download         Length: 153 bp

>AT222976 NZ_CP118233:c4989192-4988983 [Micromonospora chalcea]
ATGACCAAGATCCTGGTGGACGTCGACGACGAGGCGCTGGCGGATGCCGCCGAGGCGTTCGGCACGAAGACCAAGAAGGA
CACGGTGAACGTCGCTCTCCGCGAGGGCGCGGCGAGACTGCGCCGCGCCCGGGCACTGGCGGAGCTGGCCGAACGCGGGC
AGGCCGGTGACTTCGACGAACTGCTCGACAAGGGTGCCTACCGCTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A0K2ZNU2

References