Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 1086300..1086757 Replicon chromosome
Accession NZ_CP086333
Organism Xanthomonas translucens pv. arrhenatheri strain LMG 727

Toxin (Protein)


Gene name relE Uniprot ID A0A0K3A4N2
Locus tag KM317_RS04630 Protein ID WP_053836343.1
Coordinates 1086300..1086557 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A0K3A041
Locus tag KM317_RS04635 Protein ID WP_064521552.1
Coordinates 1086554..1086757 (-) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KM317_RS04600 (KM317_04600) 1081884..1082846 + 963 WP_053836347.1 DNA polymerase III subunit delta' -
KM317_RS04605 (KM317_04605) 1082843..1083196 + 354 WP_003479797.1 PilZ domain-containing protein -
KM317_RS04615 (KM317_04615) 1083755..1084048 - 294 WP_144423872.1 hypothetical protein -
KM317_RS04620 (KM317_04620) 1084045..1084548 - 504 WP_053836346.1 hypothetical protein -
KM317_RS04625 (KM317_04625) 1084957..1085331 - 375 Protein_910 ankyrin repeat domain-containing protein -
KM317_RS20255 1085522..1085653 - 132 WP_260676289.1 hypothetical protein -
KM317_RS04630 (KM317_04630) 1086300..1086557 - 258 WP_053836343.1 Txe/YoeB family addiction module toxin Toxin
KM317_RS04635 (KM317_04635) 1086554..1086757 - 204 WP_064521552.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KM317_RS04640 (KM317_04640) 1086856..1087991 + 1136 WP_155742827.1 IS3 family transposase -
KM317_RS04645 (KM317_04645) 1088031..1088648 - 618 WP_053836526.1 HAD-IA family hydrolase -
KM317_RS04650 (KM317_04650) 1089022..1090596 + 1575 WP_144423895.1 flavin monoamine oxidase family protein -
KM317_RS04655 (KM317_04655) 1090593..1091009 + 417 WP_053836510.1 cytochrome c -
KM317_RS04660 (KM317_04660) 1091056..1091565 + 510 WP_053836511.1 RidA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-58)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10078.55 Da        Isoelectric Point: 8.8346

>T222973 WP_053836343.1 NZ_CP086333:c1086557-1086300 [Xanthomonas translucens pv. arrhenatheri]
VTVQFSDNAWEDYLYWQQTDKKMLKRINDLIKAIQCDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYA

Download         Length: 258 bp

>T222973 NZ_CP118227:c3764655-3764236 [Proteus mirabilis]
GTGAAAAAAGTCTATATGCTTGATACAAACATTTGTTCTTTTATCATGCGTGAGCAACCTATTTCTTTGCTCGAAAAACT
TCAGAAATGTGTAATGAACCACGATACTATTGTCATATCAGCGATTACTTATTCAGAGATGCGCTTTGGAGCAATAGGAA
AAAAAGCATCACCTAAACACAATCGTTTGGTTGATGCTTTCTGTGAACGCGTTGACGCGATTTTGGCATGGGATAAAGCG
GCGGTAGACGCAACTACCGTGATAAAAAAATGCTTATCTGATGTGGGATTGCCCATAGGAAATAATGATAGCGCGATTGC
TGGTCATGCTGTCGCGGTTAATGCAATATTGGTAACAAATAATACCCGTGAATTTTCACGAGTTGAAGGACTAAAAATAG
AGGACTGGACTCATGTTTGA

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7628.72 Da        Isoelectric Point: 5.8255

>AT222973 WP_064521552.1 NZ_CP086333:c1086757-1086554 [Xanthomonas translucens pv. arrhenatheri]
MERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARDLAE

Download         Length: 204 bp

>AT222973 NZ_CP118227:c3764885-3764652 [Proteus mirabilis]
ATGAGAACGAGAACTGTAGCTGTATTTAAAAACGGAAGTAACCGAGCCATTCGCTTACCTAAAGATTTCGATTTTGATGG
TGTCAATGAACTCGAGATAAGCCGAGATGGGGATTGTATTATTTTACGCCCTGTAAAACCTAACTGGATTTCATTACAAA
ACGAAGAAAAAGCCGATAGTGATTTCTTGCTTGAACGCGATGATGTTATTGAAGAAGGACGAGTTATTCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K3A4N2

Antitoxin

Source ID Structure
AlphaFold DB A0A0K3A041

References