Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4642434..4642819 Replicon chromosome
Accession NZ_CP086332
Organism Xanthomonas translucens pv. phleipratensis strain LMG 843

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag KFS85_RS19595 Protein ID WP_003469322.1
Coordinates 4642434..4642568 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A0K2ZNU2
Locus tag KFS85_RS19600 Protein ID WP_009574163.1
Coordinates 4642667..4642819 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFS85_RS19575 (KFS85_19590) 4638775..4639698 - 924 WP_237652532.1 MBL fold metallo-hydrolase -
KFS85_RS19580 (KFS85_19595) 4639761..4641161 - 1401 WP_237652533.1 tryptophan--tRNA ligase -
KFS85_RS19585 (KFS85_19600) 4641272..4641949 + 678 WP_237652534.1 hypothetical protein -
KFS85_RS19590 (KFS85_19605) 4642020..4642235 - 216 WP_237652535.1 CsbD family protein -
KFS85_RS19595 (KFS85_19610) 4642434..4642568 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
KFS85_RS19600 (KFS85_19615) 4642667..4642819 - 153 WP_009574163.1 entericidin A/B family lipoprotein Antitoxin
KFS85_RS19605 (KFS85_19620) 4642965..4643888 - 924 WP_053838580.1 arginase -
KFS85_RS19615 (KFS85_19630) 4644312..4645154 - 843 WP_053838563.1 SPOR domain-containing protein -
KFS85_RS19620 (KFS85_19635) 4645164..4645904 - 741 WP_053838564.1 type III pantothenate kinase -
KFS85_RS19625 (KFS85_19640) 4645901..4646878 - 978 WP_237652536.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
KFS85_RS19630 (KFS85_19645) 4647029..4647301 + 273 WP_237652537.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T222972 WP_003469322.1 NZ_CP086332:c4642568-4642434 [Xanthomonas translucens pv. phleipratensis]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T222972 NZ_CP118227:3400311-3400589 [Proteus mirabilis]
ATGTACGCAATATCATTTGATTTAACCGTTGCAGATACAGAAAAACACCATCCGAAAGGCGTGTCACAGGCTTACAACGA
TATAAGTTCGACCCTTAAAAGGTACGGATTTGAGCGAATCCAGGGGAGCCTGTACACAAATAGCGATGAAAATATGGCAA
ATCTTTTTCAGGCTATGAACGCATTAAAAGCTCTTGAATGGTTCCCAAATTCAGTCAGGGATATCAGAGCATTCAGGATT
GAACAGTGGTCTGACTTCACTTCGTCTATGAAGGGTTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5393.44 Da        Isoelectric Point: 8.1210

>AT222972 WP_009574163.1 NZ_CP086332:c4642819-4642667 [Xanthomonas translucens pv. phleipratensis]
MKRLFTLMMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVENKADDCKDGKC

Download         Length: 153 bp

>AT222972 NZ_CP118227:3400119-3400307 [Proteus mirabilis]
ATGAATACAGTGCAGATTCCAACAGGTTCGATTAAGACATTCGGGCTGTTTGGTATTCCTTACGAGGTAGGGGAACCAGC
ACAGGAACTTCCCGATGGTGATATTCTTGTCAACATTATACTGGTTCAGACTGGTGAGAAAGAGCTGTACAAACTTTCAA
AACTATTACAGGATCCTGATGCAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A0K2ZNU2

References