Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3687736..3688241 Replicon chromosome
Accession NZ_CP086332
Organism Xanthomonas translucens pv. phleipratensis strain LMG 843

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KFS85_RS15100 Protein ID WP_039007339.1
Coordinates 3687984..3688241 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag KFS85_RS15095 Protein ID WP_003468816.1
Coordinates 3687736..3687987 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFS85_RS15070 (KFS85_15090) 3684284..3684568 - 285 WP_237652120.1 hypothetical protein -
KFS85_RS15075 (KFS85_15095) 3685220..3685774 + 555 WP_237652121.1 hypothetical protein -
KFS85_RS15080 (KFS85_15100) 3685810..3686253 - 444 WP_237652122.1 nuclear transport factor 2 family protein -
KFS85_RS15085 (KFS85_15105) 3686375..3687097 + 723 WP_064537986.1 helix-turn-helix transcriptional regulator -
KFS85_RS15090 (KFS85_15110) 3687094..3687627 - 534 Protein_2974 endonuclease -
KFS85_RS15095 (KFS85_15115) 3687736..3687987 + 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KFS85_RS15100 (KFS85_15120) 3687984..3688241 + 258 WP_039007339.1 Txe/YoeB family addiction module toxin Toxin
KFS85_RS15105 (KFS85_15125) 3688289..3688582 + 294 WP_237649425.1 hypothetical protein -
KFS85_RS15110 (KFS85_15130) 3688784..3689101 - 318 WP_237652123.1 HigA family addiction module antitoxin -
KFS85_RS15115 (KFS85_15135) 3689218..3689496 - 279 WP_237653799.1 type II toxin-antitoxin system RelE/ParE family toxin -
KFS85_RS15120 (KFS85_15140) 3689562..3689849 - 288 WP_237652124.1 hypothetical protein -
KFS85_RS15125 (KFS85_15145) 3689944..3690237 + 294 WP_237652125.1 hypothetical protein -
KFS85_RS20820 3690379..3690504 + 126 WP_272929820.1 hypothetical protein -
KFS85_RS15130 (KFS85_15150) 3690553..3691299 - 747 WP_237652126.1 hypothetical protein -
KFS85_RS15135 (KFS85_15155) 3691368..3691808 + 441 WP_237652127.1 helix-turn-helix domain-containing protein -
KFS85_RS15140 (KFS85_15160) 3691894..3692265 + 372 WP_237652128.1 hypothetical protein -
KFS85_RS15150 (KFS85_15170) 3692651..3693004 - 354 WP_003479797.1 PilZ domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10111.57 Da        Isoelectric Point: 9.3759

>T222970 WP_039007339.1 NZ_CP086332:3687984-3688241 [Xanthomonas translucens pv. phleipratensis]
VTVQFSDNAWEDDLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYV

Download         Length: 258 bp

>T222970 NZ_CP118227:c3349933-3348995 [Proteus mirabilis]
ATGGATAAAGATAGCCCATATTACAAACAGGTTTCCTTGCTCATAAGAATGCTTCCTGTGGTAGCGACAGAGACGGTTTT
TGCACTTAAAGGTGGCACTGCTATTAATTTATTTGTGAGAGATTTTCCTCGGTTATCTGTAGATATTGATCTTGCTTATC
TTCCACTTGAACCAAGAGATGAGGCTTTGATTAATGTCAGGGCTGCATTGCAGCGCATTACAGACAGAATCAATACTCAA
CCAGATATCAGAGCGGCATTTCAGGATAATAAAGCTGATGAACTGAGAATAGTTGTATCAAGTCCGGTTGCAACGATCAA
AATTGAAGTGTCGCCCGTCGCCAGAGGTACATTGCATAGTGCAGAAATAATGCCAGTTCAAGAGTCTGTTGAAGACGAGT
TTGGTTATGCTGAGATTCAGGTAGTCAGTCTTCCCGATCTGTATGGTGGGAAATTGTGTGCTGCAATGGATCGCCAACAT
CCTCGCGACTTATTTGATGTGCGTATGTTACTTGGCAGTGAAGGGATTTCGAGAGAGATTTTGGTGGGTTTTTTAACCTA
TACATTAAGTCACCCTCGGCCTATTAATGAAGTCATGTCGCCAAACTGGCAGCCTCTGAATGAGAAATTTCAGGCAGAAT
TTGACGGAATGACTTTTGAAAAAGTTGAATGCGAAGACTTAGCCTCTGTTAGGCCCATGATGTTAATTGAACTGCAAAAA
CATTTCACAGAAAGGGATCATGCTTTCCTTATGTCATTCAAAAGAGGGCAACCTGACTGGGCATTGTTTGACTATCCTAA
TGCAGCAGACTTGCCAGCGATTCGTTGGAAGTTGCAGAACATAAACAAATTGGCAAAGAATCAAGCAAAACATCAAGAGC
AATTAGATAAATTGAAGCAAGTACTTGATGATTGGCTTGTTAACGCAAACGCTGAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT222970 WP_003468816.1 NZ_CP086332:3687736-3687987 [Xanthomonas translucens pv. phleipratensis]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT222970 NZ_CP118227:c3350717-3349926 [Proteus mirabilis]
ATGTCATCTAAAATAAACTGGCTTGTTGCTCATACTTCTCCTGGTGCGCTAGTACTTCAGCAATGGCTGACTGAAAACGG
CGTGAGCTACTCGTTGGCTCAAAAGTACGCGCAGAACGGTTGGCTGAAGAAGCTTAGTTCTGGTGTGTACTATCGTCCAA
ATGCGCAGGGCGATATAAAGCCAACTTGGGTTGATGCCATTCAAGCATTGGATGTGCAATTGGGCGTTCCAGTTCATTTG
GCTGGACTGAGCAGCTTAACTCACCAAGGACTGAGTCACTATTTACAGCTGAACAAAGAGCAAGTTTGGATTTGCGTTAA
AAACAAGTCGTCCTTACCGAAATGGTTTCGTGAATTCCCTTATCAGAATTGGTTTTACTGTGGAAACCATAAGCTTGAAG
TGAATCCCGAGAAAGATTTGAAAAGGATCACGGTTAAAGAGAAAGAACTCACTGTCAGCTGTGCAGAACTTGCTGCCTAT
GAAGTGGTAGATGCGATTGGAAAGCTGATTTCATTTGAGCATGTCGCAGAATTATTTCAGGGTTTAGTCAATCTTAGCCC
TAGAAAAGTACAAGATATTCTTGAACGAAGCAGCTCTGTTCAGGCAAACCGAATATTTCTATTTCTGGGTCGATACTACG
ATCACCAGTGGGTCAATCGCGTAGATGAAACAAGAATTAAATTGGGGGCAGGAAAGCGGCAGGTTGTCGAAAAAGGACGT
TTTGATGAGCGATATCAAATCACAGTGCCAGAGATATTAAGCGTCAAAAAAGGTGAACAACATAATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References