Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | parDE/ParE-RHH |
| Location | 893378..893912 | Replicon | chromosome |
| Accession | NZ_CP086303 | ||
| Organism | Burkholderia sp. B21-005 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | LMA02_RS34490 | Protein ID | WP_228910342.1 |
| Coordinates | 893378..893677 (-) | Length | 100 a.a. |
Antitoxin (Protein)
| Gene name | parD | Uniprot ID | - |
| Locus tag | LMA02_RS34495 | Protein ID | WP_175662181.1 |
| Coordinates | 893667..893912 (-) | Length | 82 a.a. |
Genomic Context
Location: 892596..893071 (476 bp)
Type: Others
Protein ID: Protein_790
Type: Others
Protein ID: Protein_790
Location: 897927..898652 (726 bp)
Type: Others
Protein ID: WP_228910344.1
Type: Others
Protein ID: WP_228910344.1
Location: 888997..890346 (1350 bp)
Type: Others
Protein ID: WP_228910340.1
Type: Others
Protein ID: WP_228910340.1
Location: 890771..891721 (951 bp)
Type: Others
Protein ID: WP_228910341.1
Type: Others
Protein ID: WP_228910341.1
Location: 891883..892296 (414 bp)
Type: Others
Protein ID: WP_011660963.1
Type: Others
Protein ID: WP_011660963.1
Location: 893378..893677 (300 bp)
Type: Toxin
Protein ID: WP_228910342.1
Type: Toxin
Protein ID: WP_228910342.1
Location: 893667..893912 (246 bp)
Type: Antitoxin
Protein ID: WP_175662181.1
Type: Antitoxin
Protein ID: WP_175662181.1
Location: 894232..894714 (483 bp)
Type: Others
Protein ID: WP_175676112.1
Type: Others
Protein ID: WP_175676112.1
Location: 894983..895441 (459 bp)
Type: Others
Protein ID: WP_228910343.1
Type: Others
Protein ID: WP_228910343.1
Location: 895683..896708 (1026 bp)
Type: Others
Protein ID: WP_228910954.1
Type: Others
Protein ID: WP_228910954.1
Location: 896915..897799 (885 bp)
Type: Others
Protein ID: WP_166721721.1
Type: Others
Protein ID: WP_166721721.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LMA02_RS34470 (LMA02_34485) | 888997..890346 | - | 1350 | WP_228910340.1 | reverse transcriptase family protein | - |
| LMA02_RS34475 (LMA02_34490) | 890771..891721 | - | 951 | WP_228910341.1 | SDR family oxidoreductase | - |
| LMA02_RS34480 (LMA02_34495) | 891883..892296 | - | 414 | WP_011660963.1 | DoxX family protein | - |
| LMA02_RS34485 (LMA02_34500) | 892596..893071 | + | 476 | Protein_790 | error-prone DNA polymerase | - |
| LMA02_RS34490 (LMA02_34505) | 893378..893677 | - | 300 | WP_228910342.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LMA02_RS34495 (LMA02_34510) | 893667..893912 | - | 246 | WP_175662181.1 | type II toxin-antitoxin system ParD family antitoxin | Antitoxin |
| LMA02_RS34500 (LMA02_34515) | 894232..894714 | - | 483 | WP_175676112.1 | hypothetical protein | - |
| LMA02_RS34505 (LMA02_34520) | 894983..895441 | - | 459 | WP_228910343.1 | MEKHLA domain-containing protein | - |
| LMA02_RS34510 (LMA02_34525) | 895683..896708 | - | 1026 | WP_228910954.1 | lysozyme inhibitor LprI family protein | - |
| LMA02_RS34515 (LMA02_34530) | 896915..897799 | - | 885 | WP_166721721.1 | LysR family transcriptional regulator | - |
| LMA02_RS34520 (LMA02_34535) | 897927..898652 | + | 726 | WP_228910344.1 | pirin family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 100 a.a. Molecular weight: 11835.39 Da Isoelectric Point: 6.4868
>T222954 WP_228910342.1 NZ_CP086303:c893677-893378 [Burkholderia sp. B21-005]
MPIEARLVRLTPLAEADLEDIWTYTFERWSLEQAEHYVGELASAFERLARREWRGRPSRAGNGYWRYMVGSHVVFYRETA
ESLDVIRVLHQRMDVDRHL
MPIEARLVRLTPLAEADLEDIWTYTFERWSLEQAEHYVGELASAFERLARREWRGRPSRAGNGYWRYMVGSHVVFYRETA
ESLDVIRVLHQRMDVDRHL
Download Length: 300 bp
>T222954 NZ_CP118167:c2187053-2186877 [Bacillus subtilis]
GTGCTTGAGAAAGTGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCAGATAA
GTGCTTGAGAAAGTGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCAGATAA
Antitoxin
Download Length: 82 a.a. Molecular weight: 8836.83 Da Isoelectric Point: 5.6726
>AT222954 WP_175662181.1 NZ_CP086303:c893912-893667 [Burkholderia sp. B21-005]
MARNTSISLGDHLTQFVDTQVASGRYGSASDVVRAGLRLLETQETELRALQEALKAGEASGEPTAFDSQAFLERMRKKHA
D
MARNTSISLGDHLTQFVDTQVASGRYGSASDVVRAGLRLLETQETELRALQEALKAGEASGEPTAFDSQAFLERMRKKHA
D
Download Length: 246 bp
>AT222954 NZ_CP118167:2186994-2187094 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT