Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vagCD/VapC-VagC |
| Location | 1750443..1751128 | Replicon | chromosome |
| Accession | NZ_CP086301 | ||
| Organism | Burkholderia sp. B21-005 | ||
Toxin (Protein)
| Gene name | vagD | Uniprot ID | - |
| Locus tag | LMA02_RS08230 | Protein ID | WP_228907579.1 |
| Coordinates | 1750706..1751128 (+) | Length | 141 a.a. |
Antitoxin (Protein)
| Gene name | vagC | Uniprot ID | - |
| Locus tag | LMA02_RS08225 | Protein ID | WP_228907578.1 |
| Coordinates | 1750443..1750709 (+) | Length | 89 a.a. |
Genomic Context
Location: 1745934..1748222 (2289 bp)
Type: Others
Protein ID: WP_228907575.1
Type: Others
Protein ID: WP_228907575.1
Location: 1748309..1749148 (840 bp)
Type: Others
Protein ID: WP_228907576.1
Type: Others
Protein ID: WP_228907576.1
Location: 1749148..1750164 (1017 bp)
Type: Others
Protein ID: WP_228907577.1
Type: Others
Protein ID: WP_228907577.1
Location: 1750443..1750709 (267 bp)
Type: Antitoxin
Protein ID: WP_228907578.1
Type: Antitoxin
Protein ID: WP_228907578.1
Location: 1750706..1751128 (423 bp)
Type: Toxin
Protein ID: WP_228907579.1
Type: Toxin
Protein ID: WP_228907579.1
Location: 1753471..1754634 (1164 bp)
Type: Others
Protein ID: WP_228907581.1
Type: Others
Protein ID: WP_228907581.1
Location: 1751171..1752076 (906 bp)
Type: Others
Protein ID: WP_228907580.1
Type: Others
Protein ID: WP_228907580.1
Location: 1752045..1753136 (1092 bp)
Type: Others
Protein ID: WP_267478976.1
Type: Others
Protein ID: WP_267478976.1
Location: 1754665..1755990 (1326 bp)
Type: Others
Protein ID: WP_228907582.1
Type: Others
Protein ID: WP_228907582.1
Loading, please wait
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LMA02_RS08210 (LMA02_08220) | 1745934..1748222 | + | 2289 | WP_228907575.1 | TonB-dependent siderophore receptor | - |
| LMA02_RS08215 (LMA02_08225) | 1748309..1749148 | + | 840 | WP_228907576.1 | formyltransferase family protein | - |
| LMA02_RS08220 (LMA02_08230) | 1749148..1750164 | + | 1017 | WP_228907577.1 | GNAT family N-acetyltransferase | - |
| LMA02_RS08225 (LMA02_08235) | 1750443..1750709 | + | 267 | WP_228907578.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| LMA02_RS08230 (LMA02_08240) | 1750706..1751128 | + | 423 | WP_228907579.1 | PIN domain-containing protein | Toxin |
| LMA02_RS08235 (LMA02_08245) | 1751171..1752076 | - | 906 | WP_228907580.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| LMA02_RS08240 (LMA02_08250) | 1752045..1753136 | - | 1092 | WP_267478976.1 | type IV toxin-antitoxin system AbiEi family antitoxin | - |
| LMA02_RS08245 (LMA02_08255) | 1753471..1754634 | + | 1164 | WP_228907581.1 | M20 aminoacylase family protein | - |
| LMA02_RS08250 (LMA02_08260) | 1754665..1755990 | - | 1326 | WP_228907582.1 | cobyrinate a,c-diamide synthase | - |
Associated MGEs
Loading, please wait
MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 141 a.a. Molecular weight: 14758.86 Da Isoelectric Point: 7.8895
>T222947 WP_228907579.1 NZ_CP086301:1750706-1751128 [Burkholderia sp. B21-005]
VTTLYMLDTNICSFIMRERPSAVLSRLQSCVNAQHRIVVSAITYAEMRFGAVGRKASPKHAELVTAFVTRLDGVLSWDTA
AVDATAAIRVDLAARGTPIGANDASIAGHAIAAGAVLVTNNSREFSRVAGLSLEDWAASA
VTTLYMLDTNICSFIMRERPSAVLSRLQSCVNAQHRIVVSAITYAEMRFGAVGRKASPKHAELVTAFVTRLDGVLSWDTA
AVDATAAIRVDLAARGTPIGANDASIAGHAIAAGAVLVTNNSREFSRVAGLSLEDWAASA
Download Length: 423 bp
>T222947 NZ_CP118165:2191222-2191398 [Glaesserella parasuis]
GTGAAGCAAAGCGAATTCCTTAGGTGGCTAAAGGCTAACGGGGTAGAAGTTGAGAATGGCACAAAACATTTAAAGCTCTA
CTACAACGGCAAAAGAAGCCACCTCCCCAAACACCCTAGCCAAGAGTTAAAAACTGGTTTAGTGGAAGGGGTTAAAAAGC
AACTAGGCTTAAAATAA
GTGAAGCAAAGCGAATTCCTTAGGTGGCTAAAGGCTAACGGGGTAGAAGTTGAGAATGGCACAAAACATTTAAAGCTCTA
CTACAACGGCAAAAGAAGCCACCTCCCCAAACACCCTAGCCAAGAGTTAAAAACTGGTTTAGTGGAAGGGGTTAAAAAGC
AACTAGGCTTAAAATAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10043.33 Da Isoelectric Point: 4.5386
>AT222947 WP_228907578.1 NZ_CP086301:1750443-1750709 [Burkholderia sp. B21-005]
MRTVSIFKNARNQAIRIPKDMEFEGVTELEIRREGDTLLLRPVRPTWLSFASEPRADADFLVERPTVVELGRFDLPGADD
DAPTESNR
MRTVSIFKNARNQAIRIPKDMEFEGVTELEIRREGDTLLLRPVRPTWLSFASEPRADADFLVERPTVVELGRFDLPGADD
DAPTESNR
Download Length: 267 bp
>AT222947 NZ_CP118165:2191456-2191872 [Glaesserella parasuis]
ATGTTTTATCCAGCGTTATTTACCCCTGCCGAAGAAGGGGGATTTGTGGTGACATTTCCAGATATTCCAGAAGCGATCAC
TCAAGGTGATACATTTGAAGAAGCGATGGAAATGGCTGAAGATGTTTTATTATCTAGTGTAGAAATCTATTTCGATGATG
AGCGAGCGTTCCCGCTATCACGCCCTGCTGGAATTTATGAAACATCTGTGTTTATACCAGAGAGCGTTTATGCGAAAATT
TTACTGCACAACACTATGTGCGAAAAATTTATCTCAAAAGCAGAAGTTGCTCGCCTAAATAATATTAAGCCGCCAGAAAT
CCATCGGATTTTAGCCCCAAGACATACAACTAGGATTGACACGATTGGCAGAATCTTGGCAAGTCTTGGCAGACCATTGC
AGCTATCGCTTGCTTAA
ATGTTTTATCCAGCGTTATTTACCCCTGCCGAAGAAGGGGGATTTGTGGTGACATTTCCAGATATTCCAGAAGCGATCAC
TCAAGGTGATACATTTGAAGAAGCGATGGAAATGGCTGAAGATGTTTTATTATCTAGTGTAGAAATCTATTTCGATGATG
AGCGAGCGTTCCCGCTATCACGCCCTGCTGGAATTTATGAAACATCTGTGTTTATACCAGAGAGCGTTTATGCGAAAATT
TTACTGCACAACACTATGTGCGAAAAATTTATCTCAAAAGCAGAAGTTGCTCGCCTAAATAATATTAAGCCGCCAGAAAT
CCATCGGATTTTAGCCCCAAGACATACAACTAGGATTGACACGATTGGCAGAATCTTGGCAAGTCTTGGCAGACCATTGC
AGCTATCGCTTGCTTAA