Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 171902..172436 Replicon chromosome
Accession NZ_CP086296
Organism Burkholderia sp. B21-007

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LMA01_RS31785 Protein ID WP_228910342.1
Coordinates 172137..172436 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag LMA01_RS31780 Protein ID WP_175662181.1
Coordinates 171902..172147 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMA01_RS31755 (LMA01_31780) 167162..167887 - 726 WP_228910344.1 pirin family protein -
LMA01_RS31760 (LMA01_31785) 168015..168899 + 885 WP_166721721.1 LysR family transcriptional regulator -
LMA01_RS31765 (LMA01_31790) 169106..170131 + 1026 WP_228910954.1 lysozyme inhibitor LprI family protein -
LMA01_RS31770 (LMA01_31795) 170373..170831 + 459 WP_228910343.1 MEKHLA domain-containing protein -
LMA01_RS31775 (LMA01_31800) 171226..171582 + 357 WP_229050914.1 hypothetical protein -
LMA01_RS31780 (LMA01_31805) 171902..172147 + 246 WP_175662181.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
LMA01_RS31785 (LMA01_31810) 172137..172436 + 300 WP_228910342.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LMA01_RS31790 (LMA01_31815) 172743..173218 - 476 Protein_147 error-prone DNA polymerase -
LMA01_RS31795 (LMA01_31820) 173518..173931 + 414 WP_011660963.1 DoxX family protein -
LMA01_RS31800 (LMA01_31825) 174093..175043 + 951 WP_228910341.1 SDR family oxidoreductase -
LMA01_RS31805 (LMA01_31830) 175468..176817 + 1350 WP_228910340.1 reverse transcriptase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-94)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11835.39 Da        Isoelectric Point: 6.4868

>T222936 WP_228910342.1 NZ_CP086296:172137-172436 [Burkholderia sp. B21-007]
MPIEARLVRLTPLAEADLEDIWTYTFERWSLEQAEHYVGELASAFERLARREWRGRPSRAGNGYWRYMVGSHVVFYRETA
ESLDVIRVLHQRMDVDRHL

Download         Length: 300 bp

>T222936 NZ_CP118156:c6220125-6219832 [Pseudomonas chlororaphis]
ATGAACGAACCGCTTTTCGACTATGACCCCGCCACGGCCCTGCGTGACCCGCAAGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCATTCAGCGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGTGCACTGGGGCTGGACATGACGGCGCGGGTGCATGGGGCGTCTTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8836.83 Da        Isoelectric Point: 5.6726

>AT222936 WP_175662181.1 NZ_CP086296:171902-172147 [Burkholderia sp. B21-007]
MARNTSISLGDHLTQFVDTQVASGRYGSASDVVRAGLRLLETQETELRALQEALKAGEASGEPTAFDSQAFLERMRKKHA
D

Download         Length: 246 bp

>AT222936 NZ_CP118156:c6220421-6220122 [Pseudomonas chlororaphis]
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATTGC
TGCGCGGATTTTTCGCTTGGCCAACGGTCTTGCCGGGGACGTGTCGCCGGTGGGCGAAGGCGTCAGCGAGCTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCAGCGCGGCTTGCAACTCGTCATTCTGTTGTGCGGCGGCGACAAGAGT
CGCCAGGGCCGCGATATCGAACTGGCCAAACAGCTGGCCCGTCGTTGGAGCCGATCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References