Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 130410..130917 Replicon plasmid unnamed
Accession NZ_CP086258
Organism Providencia rettgeri strain KM4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LL668_RS20810 Protein ID WP_196719255.1
Coordinates 130642..130917 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LL668_RS20805 Protein ID WP_282564848.1
Coordinates 130410..130655 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL668_RS20780 (LL668_20820) 126428..126853 - 426 WP_228367732.1 glutaredoxin-dependent arsenate reductase -
LL668_RS20785 (LL668_20825) 126866..128155 - 1290 WP_228367733.1 arsenic transporter -
LL668_RS20790 (LL668_20830) 128200..128520 - 321 WP_004911727.1 transcriptional regulator -
LL668_RS20795 (LL668_20835) 128606..129304 + 699 WP_228367734.1 arsenical resistance protein ArsH -
LL668_RS20800 (LL668_20840) 129690..129920 + 231 WP_228367735.1 hypothetical protein -
LL668_RS20805 (LL668_20845) 130410..130655 + 246 WP_282564848.1 DUF6290 family protein Antitoxin
LL668_RS20810 (LL668_20850) 130642..130917 + 276 WP_196719255.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LL668_RS20815 (LL668_20855) 131964..132617 - 654 WP_228367736.1 nitroreductase family protein -
LL668_RS21205 132919..133065 + 147 WP_282564849.1 hypothetical protein -
LL668_RS21095 133067..133189 - 123 WP_267081383.1 hypothetical protein -
LL668_RS20820 (LL668_20860) 133774..134064 + 291 WP_228367737.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..171394 171394


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-88)

Antitoxin

Protein of unknown function DUF6290

(7-68)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11015.92 Da        Isoelectric Point: 10.2548

>T222849 WP_196719255.1 NZ_CP086258:130642-130917 [Providencia rettgeri]
MPHYRIEYTKRFQKELKKIDRCHQKIIQSYIEKNIDNSINPRLIGKILKGDKAEFIRYRIGDYRLIATIEDERLVILALS
IGHRKDVYKHF

Download         Length: 276 bp

>T222849 NZ_CP118146:784147-784443 [Pseudomonas chlororaphis]
ATGCATATCATCACCGCCAAACGAATCTGGGAGGCCAAGAGCCGCTGGCCACAATCGGCCAATGCGCTGGAAACCTGGTA
CAGAAAAGCCAAAAGCCTCAATCCGGCCGATTTTGCAGCCATCAAGGCGGTATTTCCGGCCACCGACAAAGTAGGGGCGT
TTCACGTCTTCGATATTGGTGGCAACAAGTTACGAATCATCGCCGTGGTGCGTTATGAAGTACGACGTCTCTATATCAGG
CACGTGCTGGACCATCACGAATACGACAAAGGCAGGTGGAAGGAGGAAACCAGATGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9117.26 Da        Isoelectric Point: 4.2932

>AT222849 WP_282564848.1 NZ_CP086258:130410-130655 [Providencia rettgeri]
MRKNLTKAIRLNNEELSLFESYANAKGLTFSELCKSAIIEKIEDEIDLKLAEEAYEEYLNDSETLSHKAIFDPLGNYASL

Download         Length: 246 bp

>AT222849 NZ_CP118146:784440-784841 [Pseudomonas chlororaphis]
ATGAACGTTCTGGTGAAGCAGGCGGCGGATCATTGGCATTTCGTGGCGCCTGTGTTGCGTAAACCCAAGACCGAAGCCGA
TTACGATGCATTGGTCGCGGCGCTGGATGAACTGCTGGATCTCATGGGAGAGGACGAGAACCATCCAGTGACTTCGCTGG
TGGACATCATCGGCGACTGGATCGAAGCCTACGACGAAGAGCATCGACCGATGCCGATAGCCAGTGGTGTTGACGTCTTG
CGCTCCCTGATGCGCGAACACGGCCTGACCCAGAGCGATCTGCCAGGCGTGGGTGCACAGTCGGTGGTTTCCGAAGTGCT
GAGCGGCAAGCGCCAGCTCAACCTGCGGCAGATCCGCTGGCTGGCCGAGCGCTTCGGTGTTTCGGCCGAGGTCTTTATCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References