Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 4274396..4274942 Replicon chromosome
Accession NZ_CP086257
Organism Providencia rettgeri strain KM4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LL668_RS19730 Protein ID WP_228367322.1
Coordinates 4274661..4274942 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LL668_RS19725 Protein ID WP_102140619.1
Coordinates 4274396..4274680 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL668_RS19700 (LL668_19735) 4269471..4270448 - 978 WP_004265237.1 6-phosphofructokinase -
LL668_RS19705 (LL668_19740) 4270854..4271798 - 945 WP_109912960.1 phosphatidate cytidylyltransferase -
LL668_RS19710 (LL668_19745) 4271795..4272436 - 642 WP_102140622.1 lysophospholipid acyltransferase family protein -
LL668_RS19715 (LL668_19750) 4272674..4273426 - 753 WP_004907010.1 M48 family metallopeptidase -
LL668_RS19720 (LL668_19755) 4273653..4274234 - 582 WP_117162998.1 HutD family protein -
LL668_RS19725 (LL668_19760) 4274396..4274680 + 285 WP_102140619.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LL668_RS19730 (LL668_19765) 4274661..4274942 + 282 WP_228367322.1 type II toxin-antitoxin system YafQ family toxin Toxin
LL668_RS19735 (LL668_19770) 4275237..4275824 - 588 WP_004907001.1 Spy/CpxP family protein refolding chaperone -
LL668_RS19740 (LL668_19775) 4275975..4276673 + 699 WP_004907000.1 envelope stress response regulator transcription factor CpxR -
LL668_RS19745 (LL668_19780) 4276670..4278040 + 1371 WP_004906999.1 envelope stress sensor histidine kinase CpxA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(9-84)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10956.75 Da        Isoelectric Point: 9.1315

>T222848 WP_228367322.1 NZ_CP086257:4274661-4274942 [Providencia rettgeri]
MLKTRVKSQFKKDLKKSLSDKKRNTQLLKELIDNHLCITGSVPAEYLPHPLKGNWRPCYEYHIQPDFLLIWDINYQTNEI
ILVRCGSHSELFG

Download         Length: 282 bp

>T222848 NZ_CP118146:c570664-570236 [Pseudomonas chlororaphis]
ATGATCGTGCTCGACACTAATGTGCTGTCGGAACTGATGCGTCCCCAACCGGACGCATCGGTATTGCTGTGGATCGAAGC
GCAACCTGTCGAAGACCTCTACATCAGCGCCATGACCATGGCCGAGATTCTTCACGGCATCGCGCGCCTGCCCCACGGCA
AGCGCAAACAGATGCTCCATGCGTCGGCGCTCGCGATGTTCGAGGAAGATTTCATCGACCGCATCGTGCCCTTCGGGACC
CAGGCGGCTCTTTACTACGCCCATCTGATTTCGCACCGGGAAAGCCTGGGGCGTCCGATCAGCCTGGTGGATGCGCAAAT
CGCGGCCATATGCCGCGTCCACGACGCGGCGATCGCCACCCGTAACGCCAAGGACTTCAGCGATACAGGGTTGATCGTTA
TCAACCCCTGGCTGCCACTCGAGGTTTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10420.71 Da        Isoelectric Point: 4.6412

>AT222848 WP_102140619.1 NZ_CP086257:4274396-4274680 [Providencia rettgeri]
MASTQHKTDIVRARIEPKVRENAEAVLSELGISMSDAIRIFVKQISLRQAFPIELKTPNSITLEAINAPTTDETFDSAED
LFSQVSKSDAENSR

Download         Length: 285 bp

>AT222848 NZ_CP118146:c570906-570661 [Pseudomonas chlororaphis]
ATGGCCAGCCTGACAATCCGAAACCTGGACGACCACATCAAAGAGCGCCTGCGCATCGAGGCCGCCCACAACGGCCACTC
CATGGAAGAAGAAGCCCGCTTGATTTTGCGCCGCGCCCTGAACAGAACAACCGACAGCCAAGGCCTGGCCAGTCGTATCC
GGGCACGCTTTGCCGAGGCCGGCGGAGTGAAGCTTGAGCTGCCCGAACGTACCGAGCCGGCACGCGTGGTGGATCTGGGC
GAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References