Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1423061..1423718 Replicon chromosome
Accession NZ_CP086257
Organism Providencia rettgeri strain KM4

Toxin (Protein)


Gene name cptA Uniprot ID A0A6G6PHM2
Locus tag LL668_RS06200 Protein ID WP_042851636.1
Coordinates 1423308..1423718 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A6G6PHM9
Locus tag LL668_RS06195 Protein ID WP_004913039.1
Coordinates 1423061..1423327 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL668_RS06180 (LL668_06185) 1420057..1420953 - 897 WP_164528562.1 hypothetical protein -
LL668_RS06185 (LL668_06190) 1421198..1421818 - 621 WP_109912916.1 HD domain-containing protein -
LL668_RS06190 (LL668_06195) 1421830..1422813 - 984 WP_004913041.1 tRNA-modifying protein YgfZ -
LL668_RS06195 (LL668_06200) 1423061..1423327 + 267 WP_004913039.1 FAD assembly factor SdhE Antitoxin
LL668_RS06200 (LL668_06205) 1423308..1423718 + 411 WP_042851636.1 protein YgfX Toxin
LL668_RS06205 (LL668_06210) 1423808..1424326 - 519 WP_004913034.1 flavodoxin FldB -
LL668_RS06210 (LL668_06215) 1424444..1425346 + 903 WP_109912915.1 site-specific tyrosine recombinase XerD -
LL668_RS06215 (LL668_06220) 1425368..1426072 + 705 WP_109912946.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LL668_RS06220 (LL668_06225) 1426082..1427815 + 1734 WP_228367509.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15612.59 Da        Isoelectric Point: 10.7733

>T222846 WP_042851636.1 NZ_CP086257:1423308-1423718 [Providencia rettgeri]
VVLWKSNLSISWKTQLFSTCVHGVIGMFLLLTPWSPGNSMIWLPLLVVVVASWAKSQKNISKIKGVAVLVNGNKLQWKKN
EWRILKAPWLTRYGILLTLEALQGKPQKIHLWVAKDALSEENWRNLNQLLLQYPDI

Download         Length: 411 bp

>T222846 NZ_CP118146:118275-119153 [Pseudomonas chlororaphis]
ATGTTGCCAGGCCTCTCTCAACCCGTATCGACGGCGGACCTCCAGGCCCGACTGACCCGGGACTTTGCCCAGCGCCAGGT
GACCGTGGCCGGCGGCCGGCAGGCCCTGCGCGAATGCGGCGCGGGCCCGGCGATCGTGCTGCTGCACGGCATCGGTTCCG
GGGCGGCGTCCTGGCTGCAGGTGGCGCAACAACTGGCGCCCCAGGCCCGGGTCATCGCCTGGGACGCGCCCGGCTACGGC
GATTCCAGCCCCCTGGAATCCCCCGCGCCCAAGGCCGAGCACTACGCCGCCCGCCTGGTGCAGATGCTCGATGCCCTGGA
CGTCGAGGAATGCGTGCTGGTGGGGCATTCCCTCGGCGCGCTGCCGGCCCTGGCCTTCGCTCGTAGTTCACAGGCGAGCC
GGGTGAGTCGCCTGGTACTGATCAGCCCGGCCCGGGGTTATGGCGCGCCGGAACGCGGCGAGCAGCGCCAGCAGGTGCGC
CGCCAGCGCCTGGAGAACCTGGAGCATCTGGGGATCACCGGCCTGGCCGAGCAACGCAGCACCCACATGCTCTCGCCCAA
CGCCGCGCCACAGGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTCAACCCCGCGGGTTATCGCCAGGCCATCGAGC
TGCTGTGCGGCGGCGACCTGCTGCGCCACGGCCAGCCCGGCATGCCCTGCGAAGTGCATTGCGGCGAGGCCGACCGCATC
ACCCCGGCCGAGACCTGCCTGACCCTGGCCAAGGCGCTGGGCGCCAGCTTCAACCTGATCGCCGACGCGGGCCATGCCAG
CCCCATCGAACAACCGCTGGTGGTCGCGGGCCGCCTGGCCTTTGCCATCAAAGAATCCCTGACAGGTAGAACCCTATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10674.24 Da        Isoelectric Point: 4.8780

>AT222846 WP_004913039.1 NZ_CP086257:1423061-1423327 [Providencia rettgeri]
MDIENKARIHWACRRGMRELDISIMPFFEYEYDNLTTQDKQVFVRLLECADPDLFNWLMNHGRPDDDELFRMIKLIQEKN
KNRGPVEI

Download         Length: 267 bp

>AT222846 NZ_CP118146:119150-119983 [Pseudomonas chlororaphis]
ATGAACGACTCCGATCCGCTGAAGGACGCTCAGGACAAATACATAGTGCCGGGCCTGGAGCGTGGCCTGTTGCTGCTCTG
CGAGTTCAGCCGGCGCAACCGCACCCTGACCGCGCCGGAACTGGCCCGCCGCCTGGCCCTGCCGCGCTCGACCATCTTTC
GCCTGCTCACCACCCTGGAAACCATGGGTTTCGTCACCCGCAGCGGCAACGAATACCGCCTCGGCATGTCGGTGCTGCGC
CTGGGCTTCGAATACCTGGCGTCGCTGGAGCTGACCGAGCTCGGCCAGCCGCTGCTGGCGCGCCTGTGCGACCGCCTCAA
CTACCCGAGCAACCTGGTGGTGCGCGACGGCCGCTCGATCGTCTACGTGGCCAAGGTCTCGCCGCCCTCGGTGTTCTCCA
ACGCGGTCAACGTCGGCACCCGCCTGCCGGCCCACGCCACGGTGCTGGGGCGCATCCTCCTGGAAGACCTGTCCCTGGCC
GAACTGCGCGAGCTGTACCCCGAAGAGCATCTGGAGCAGTACTCCCACAGCACGCCGAAAACCGTGCTGGAGCTGTTCGA
CATGGTCCAGGCCGACCGTCAGCGCGGCTTTATCAGCGGCGAAGGTTTCTTCGAATCGGCGATCTCCACGGTGGCCGCGC
CAGTGCGCGACCAGAGCGGGCGCATCGCCGCGGCCCTGGGCGTGACCATCCCCACCACGCAGATCGGCCACGTCAATTTC
GAGGAACTGCTGTCGCAGGTCCGCCGTAGCGCCGACGAGCTGTCACGCCTGCTCAACTACAACGGCGTGGCCCACGACGG
GCAACAGCGCGTGACCGCCTTGATGAGGGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6G6PHM2

Antitoxin

Source ID Structure
AlphaFold DB A0A6G6PHM9

References