Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 193299..193819 Replicon chromosome
Accession NZ_CP086254
Organism Brachybacterium halotolerans subsp. kimchii strain CBA3105

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag Bra3105_RS00880 Protein ID WP_200500941.1
Coordinates 193529..193819 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag Bra3105_RS00875 Protein ID WP_200500942.1
Coordinates 193299..193532 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Bra3105_RS00850 (Bra3105_00855) 188550..188735 - 186 WP_228358219.1 hypothetical protein -
Bra3105_RS00855 (Bra3105_00860) 188868..189716 + 849 WP_228358220.1 N-acetyltransferase -
Bra3105_RS00860 (Bra3105_00865) 189790..190086 + 297 WP_152352722.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
Bra3105_RS00865 (Bra3105_00870) 190089..191642 + 1554 WP_228358221.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
Bra3105_RS00870 (Bra3105_00875) 191642..193153 + 1512 WP_200500943.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
Bra3105_RS00875 (Bra3105_00880) 193299..193532 + 234 WP_200500942.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
Bra3105_RS00880 (Bra3105_00885) 193529..193819 + 291 WP_200500941.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Bra3105_RS00885 (Bra3105_00890) 193902..194435 + 534 WP_228358222.1 DUF664 domain-containing protein -
Bra3105_RS00890 (Bra3105_00895) 194603..195595 - 993 WP_228358223.1 hypothetical protein -
Bra3105_RS00895 (Bra3105_00900) 195716..196219 - 504 WP_228358224.1 hypothetical protein -
Bra3105_RS00900 (Bra3105_00905) 196392..198455 + 2064 WP_228358225.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(1-75)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11410.84 Da        Isoelectric Point: 9.5837

>T222842 WP_200500941.1 NZ_CP086254:193529-193819 [Brachybacterium halotolerans subsp. kimchii]
MKRFRLTPAAQRDLSEIWDFTEDRWSASQAESYLRDIQNAIERLAADPDRGRPVDDIRQGYRRYGIGSHLVFYVQRGDRI
DVIRILHQRMDPGRHL

Download         Length: 291 bp

>T222842 NZ_CP118145:c1771887-1771705 [Pseudomonas chlororaphis]
GTGGACAGTCGGTATTTGATCGGCCAAATCGTCGCAGACGGTTGGTATCTGGTCAGGGTCAGGGGCAGTCACCACCATTT
CAAGCATCCCCATAAACCGGGGCTGGTGACCGTTCCCCATCCCAAGAAGGACCTGCTGAGAAAAACCGCCATCAGTATTC
TGAAACAGGCGCTGCTCATGTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8421.27 Da        Isoelectric Point: 4.2550

>AT222842 WP_200500942.1 NZ_CP086254:193299-193532 [Brachybacterium halotolerans subsp. kimchii]
MAQNTSISLDDHYSGFLAEQVASGRYRSSSEVIRAGLRLLEDRETQLAALREALVVGEESGEAQPFDFDAFIASKQA

Download         Length: 234 bp

>AT222842 NZ_CP118145:c1771672-1771265 [Pseudomonas chlororaphis]
ATGCTTTACCCGATTGCAATTTCAATGGGCGATGACGAACACGCCTGGGGGGTGGAAGTCCCCGATATTCCTGGCTGTTT
CTCGGCCGGCGACGACCTCGACGACGCCATGGCCATGGCCCGCGAAGCCATCGAAGGGCACTTCGAGATTCTCGCTGAAG
ACGGTGCCCCCATCCCGCACGCCAACAAGGTCACCCTGCACGCGGCCAACCCCCGGTACGCAGGCTGCACCTGGGCGCTG
ATCGACATCGATGTCACCAAGTACCTGGGCAAGGCGCAGAAGCTCAACATCACCCTGCCCGGCTACTTGCTGAGCCGCAT
CGACGAATACGTGCTGCATCACCCGGAAGCCAAGAGCCGCTCGGGTTTTCTCGCTTCGGCTGCACTGAAGGTATTGCAAC
AAGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References