Detailed information of TA system TA222840

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 4321936..4322471
• Replicon: chromosome
• Accession: NZ_CP086253
• Organism: Pectobacterium aquaticum strain A212-S19-A16

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: DMB82_RS20015
• Protein ID: WP_039546296.1
• Coordinates: 4322184..4322471 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: DMB82_RS20010
• Protein ID: WP_102118771.1
• Coordinates: 4321936..4322187 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DMB82_RS19980 (DMB82_0020040)	4317084..4318118	+	1035	WP_116163881.1	putative FMN-dependent luciferase-like monooxygenase	-
DMB82_RS19985 (DMB82_0020045)	4318115..4319248	+	1134	WP_116163879.1	alkylhydroperoxidase domain protein	-
DMB82_RS19990 (DMB82_0020050)	4319435..4319761	+	327	WP_039546304.1	helix-turn-helix domain-containing protein	-
DMB82_RS19995 (DMB82_0020055)	4319746..4320060	+	315	WP_102118768.1	HipA N-terminal domain-containing protein	-
DMB82_RS20000 (DMB82_0020060)	4320057..4321097	+	1041	WP_116163877.1	HipA domain-containing protein	-
DMB82_RS20005 (DMB82_0020065)	4321156..4321670	-	515	Protein_3907	LysE family translocator	-
DMB82_RS20010 (DMB82_0020070)	4321936..4322187	+	252	WP_102118771.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
DMB82_RS20015 (DMB82_0020075)	4322184..4322471	+	288	WP_039546296.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
DMB82_RS20020 (DMB82_0020080)	4322573..4323925	-	1353	WP_102118773.1	glutathione-disulfide reductase	-
DMB82_RS20025 (DMB82_0020085)	4324052..4324894	-	843	WP_102118774.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
DMB82_RS20030 (DMB82_0020090)	4325055..4325204	-	150	Protein_3912	Hsp70 family protein	-
DMB82_RS20035 (DMB82_0020095)	4325357..4326166	-	810	WP_116163875.1	energy transducer TonB	-
DMB82_RS20040 (DMB82_0020100)	4326369..4327358	-	990	WP_102118776.1	FecR domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11014.10 Da
• Isoelectric Point: 10.3527

>T222840 WP_039546296.1 NZ_CP086253:4322184-4322471 [Pectobacterium aquaticum]
MSYSVKFREDALKEWLKLDKAIQQQFAKKLKKCCENPHIPAAKLRGMKDCYKIKLRASGFRLVYEVIDDVLVIAVVAVGK
RERSGVYHLASERMR

Nucleotide

• Length: 288 bp

>T222840 NZ_CP118145:770965-771261 [Pseudomonas chlororaphis]
ATGCATATCATCACCGCCAAACGAATCTGGGAGGCCAAGAGCCGCTGGCCACAATCGGCCAATGCGCTGGAAACCTGGTA
CAGAAAAGCCAAAAGCCTCAATCCGGCCGATTTTGCAGCCATCAAGGCGGTATTTCCGGCCACCGACAAAGTAGGGGCGT
TTCACGTCTTCGATATTGGTGGCAACAAGTTACGAATCATCGCCGTGGTGCGTTATGAAGTACGACGTCTCTATATCAGG
CACGTGCTGGACCATCACGAATACGACAAGGGCAGGTGGAAGGAGGAAACCAGATGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9145.52 Da
• Isoelectric Point: 4.0785

>AT222840 WP_102118771.1 NZ_CP086253:4321936-4322187 [Pectobacterium aquaticum]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELIKLIGERKNQPLVEVDLD
SFL

Nucleotide

• Length: 252 bp

>AT222840 NZ_CP118145:771258-771659 [Pseudomonas chlororaphis]
ATGAACGTTCTGGTGAAGCAGGCGGCGGATCATTGGCATTTCGTGGCGCCTGTGTTGCGTAAACCCAAGACCGAAGCCGA
TTACGATGCATTGGTCGCGGCGCTGGATGAACTGCTGGATCTCATGGGAGAGGACGAGAACCATCCAGTGACTTCGCTGG
TGGACATCATTGGCGACTGGATCGAAGCCTACGACGAAGAGCATCGACCGATGCCGATAGCCAGTGGTGTTGACGTCTTG
CGCTCCCTGATGCGCGAACACGGCCTGACCCAGAGCGATCTGCCAGGCGTGGGTGCACAGTCGGTGGTTTCCGAAGTGCT
GAGCGGCAAGCGCCAGCTCAACCTGCGGCAGATCCGCTGGCTGGCCGAGCGCTTCGGTGTTTCGGCCGAGGTCTTTATCT
GA