Detailed information of TA system TA222838

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 4255974..4257414
• Replicon: chromosome
• Accession: NZ_CP086253
• Organism: Pectobacterium aquaticum strain A212-S19-A16

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: DMB82_RS19695
• Protein ID: WP_116162847.1
• Coordinates: 4255974..4256861 (-)
• Length: 296 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: -
• Locus tag: DMB82_RS19700
• Protein ID: WP_095993166.1
• Coordinates: 4256890..4257414 (-)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DMB82_RS19670 (DMB82_0019730)	4251254..4252162	+	909	WP_102117031.1	LysR family transcriptional regulator	-
DMB82_RS19675 (DMB82_0019735)	4252261..4253124	+	864	WP_102117032.1	YicC/YloC family endoribonuclease	-
DMB82_RS19680 (DMB82_0019740)	4253316..4253820	+	505	Protein_3842	Arm DNA-binding domain-containing protein	-
DMB82_RS19685 (DMB82_0019745)	4253878..4254572	+	695	WP_102117033.1	IS1 family transposase	-
DMB82_RS19690 (DMB82_0019750)	4254928..4255752	+	825	WP_102117034.1	DNA damage-inducible protein D	-
DMB82_RS19695 (DMB82_0019755)	4255974..4256861	-	888	WP_116162847.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
DMB82_RS19700 (DMB82_0019760)	4256890..4257414	-	525	WP_095993166.1	hypothetical protein	Antitoxin
DMB82_RS19705 (DMB82_0019765)	4257517..4258635	-	1119	WP_116162849.1	hypothetical protein	-
DMB82_RS19710 (DMB82_0019770)	4258646..4259644	-	999	WP_116162851.1	SEC-C domain-containing protein	-
DMB82_RS19715 (DMB82_0019775)	4259766..4260057	-	292	Protein_3849	helix-turn-helix transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	4253878..4277962	24084

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (36-265)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 296 a.a.
• Molecular weight: 33970.87 Da
• Isoelectric Point: 5.9863

>T222838 WP_116162847.1 NZ_CP086253:c4256861-4255974 [Pectobacterium aquaticum]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIMDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFQPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYNIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFISKQIKERTLDNPAYWAYVQGEVHAIASELLNDGTPKNPFDMG

Nucleotide

• Length: 888 bp

>T222838 NZ_CP118145:430146-430427 [Pseudomonas chlororaphis]
ATGACTTATAAGCTCCAGTTTCTGCCTTCGGCACGTAAGGAATGGGACAAGCTCGGTCATACCCTGCGCGAGCAATTCAA
GAAGAAGCTGGCCGAGCGCCTGGAAATGCCACGGGTGCCCGCGGATGCCCTTCACGGCATGGCGGACTGCTACAAGATCA
AGCTCAAGGCCTCTGGCTATCGCCTGGTTTACCAAGTGATCGAGGATCAGGTGGTGGTTTCGGTGGTGGCCGTGGGCAAA
CGTGAACGCAGCGCCGTGTATGAGCGGGCACGAAAGCGCTGA

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19339.48 Da
• Isoelectric Point: 9.0504

>AT222838 WP_095993166.1 NZ_CP086253:c4257414-4256890 [Pectobacterium aquaticum]
MAKSDELLNALAKAVNAGGGIHSVTELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLSYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES

Nucleotide

• Length: 525 bp

>AT222838 NZ_CP118145:429911-430156 [Pseudomonas chlororaphis]
ATGCAAAGCGTATTGGCTGATAAAGCTGTCAGCGTGTCTGAACTGAAAAAAAACCCCTCGGCTGTCCTGAGCGGCGCACA
CGGTGGTCCGGTTGCGGTGCTCAATCACAACCGGGTCATGGGCTATATGGTCCCGGCCGACGTGTTTGAAGCCATGATGG
AGCGTCTTGACGATCTTGAACTGGCGGAGATTGTCCGTGCCCGTCGGCACGAGACCCCTGTCCCGGTAAATCTGGATGAC
TTATAA