222837

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3719134..3719684 Replicon chromosome
Accession NZ_CP086253
Organism Pectobacterium aquaticum strain A212-S19-A16

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag DMB82_RS17230 Protein ID WP_116163751.1
Coordinates 3719376..3719684 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag DMB82_RS17225 Protein ID WP_116163749.1
Coordinates 3719134..3719373 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DMB82_RS17205 (DMB82_0017260) 3714576..3714887 - 312 WP_102117372.1 AzlD domain-containing protein -
DMB82_RS17210 (DMB82_0017265) 3714884..3715618 - 735 WP_102117373.1 AzlC family ABC transporter permease -
DMB82_RS17215 (DMB82_0017270) 3715758..3716594 - 837 WP_116163745.1 AraC family transcriptional regulator -
DMB82_RS17220 (DMB82_0017275) 3716809..3718428 - 1620 WP_116163747.1 methyl-accepting chemotaxis protein -
DMB82_RS17225 (DMB82_0017280) 3719134..3719373 + 240 WP_116163749.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
DMB82_RS17230 (DMB82_0017285) 3719376..3719684 + 309 WP_116163751.1 CcdB family protein Toxin
DMB82_RS17235 (DMB82_0017290) 3719829..3719993 - 165 WP_102117376.1 glucose uptake inhibitor SgrT -
DMB82_RS17240 (DMB82_0017295) 3720084..3721742 + 1659 WP_102117377.1 HTH-type transcriptional regulator SgrR -
DMB82_RS17245 (DMB82_0017300) 3721960..3722940 + 981 WP_145985147.1 thiamine ABC transporter substrate binding subunit -
DMB82_RS17250 (DMB82_0017305) 3722916..3724523 + 1608 WP_116163755.1 thiamine/thiamine pyrophosphate ABC transporter permease ThiP -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(9-79)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11762.59 Da        Isoelectric Point: 9.3356

>T222837 WP_116163751.1 NZ_CP086253:3719376-3719684 [Pectobacterium aquaticum]
MQYKVYRNNGNSNSYPYLLNIQSDIIGELHTRLVIPLFPLHKIARPPARRLTPIVTVEGNDYLIMTHEMASVRRSQLGNE
VMDAQVYRKTIKDAVDFLLDGF

Download         Length: 309 bp

>T222837 NZ_CP118144:c6352305-6352006 [Pseudomonas chlororaphis]
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATTGC
TGCGCGGATTTTTCGCCTGGCCAACGGTCTTGCCGGGGACGTGTCGCCGGTGGGCGAAGGCGTCAGTGAGCTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCAGCGCGGCTTGCAACTCGTCATCCTGTTGTGCGGCGGCGACAAGAGT
CGCCAGGGCCGCGATATCGAACTGGCCAAACAGCTGGCCCGTCGTTGGAGCCGATCATGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8964.30 Da        Isoelectric Point: 10.3884

>AT222837 WP_116163749.1 NZ_CP086253:3719134-3719373 [Pectobacterium aquaticum]
MPVTSVRHKKTVSVTLEPVLLQQAREAGINLSAILTEALKREIRLSEGEKWKQQNQKALQELNRITDKHGLLSDDGRTF

Download         Length: 240 bp

>AT222837 NZ_CP118144:c6352009-6351716 [Pseudomonas chlororaphis]
ATGAACGAACCGCTTTTCGACTATGACCCCGCCACGGCCCTGCGCGACCCGCAGGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCATTCAGCGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGTGCACTGGGGCTGGACATGACGGCGCGGGTGCATGGGGCGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References