Detailed information of TA system TA222835

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mosAT/AbiEii-AbiEi
• Location: 3323321..3325004
• Replicon: chromosome
• Accession: NZ_CP086253
• Organism: Pectobacterium aquaticum strain A212-S19-A16

Toxin (Protein)

• Gene name: mosT
• Uniprot ID: -
• Locus tag: DMB82_RS15420
• Protein ID: WP_105879248.1
• Coordinates: 3323321..3324238 (-)
• Length: 306 a.a.

Antitoxin (Protein)

• Gene name: mosA
• Uniprot ID: A0A3R8N1C1
• Locus tag: DMB82_RS15425
• Protein ID: WP_044206245.1
• Coordinates: 3324231..3325004 (-)
• Length: 258 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DMB82_RS15390 (DMB82_0015440)	3318631..3319398	+	768	WP_116164559.1	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	-
DMB82_RS15395 (DMB82_0015445)	3319595..3320224	+	630	WP_116156100.1	glutathione S-transferase	-
DMB82_RS15400 (DMB82_0015450)	3320483..3320962	+	480	WP_010296476.1	Hcp family type VI secretion system effector	-
DMB82_RS15405 (DMB82_0015455)	3321034..3321369	+	336	WP_039557101.1	hypothetical protein	-
DMB82_RS15410 (DMB82_0015460)	3321362..3321706	+	345	WP_116164557.1	hypothetical protein	-
DMB82_RS15415 (DMB82_0015465)	3321721..3322515	-	795	WP_116156346.1	DUF4225 domain-containing protein	-
DMB82_RS15420 (DMB82_0015470)	3323321..3324238	-	918	WP_105879248.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
DMB82_RS15425 (DMB82_0015475)	3324231..3325004	-	774	WP_044206245.1	type IV toxin-antitoxin system AbiEi family antitoxin	Antitoxin
DMB82_RS15435 (DMB82_0015485)	3326100..3329537	-	3438	WP_125176142.1	AAA domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3321034..3350870	29836

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (14-279)

Antitoxin

• Transcriptional regulator AbiEi antitoxin, N-terminal domain (1-93)

Sequences

Toxin

Protein

• Length: 306 a.a.
• Molecular weight: 34425.65 Da
• Isoelectric Point: 4.9438

>T222835 WP_105879248.1 NZ_CP086253:c3324238-3323321 [Pectobacterium aquaticum]
MDKQSPYYRQVALLLSALPVVASERCFALKGGTAINLFVRDFPRLSVDIDLAYIPLESRDVALPNVRAALTRIAEILQQQ
VGISAVLQTNNPDEMRIVVSSPEAQIKIEVSPVARGTLYPPEERDVVEAVEDEFGFATIPVVSLADLYGGKLCAALDRQH
PRDFYDVKMLLETQGIDRHIFNGFITYLLGHKRPLSEILDPHWKDISLPYANEFNGMTFDTVSLEELNAIPNLMVTALKA
QFTQQDYDFLMSFKSGQPDWSLAPEDQIQHLPAVKWKLQNIVRIPKDKHIQALAKLETVLAEWIR

Nucleotide

• Length: 918 bp

>T222835 NZ_CP118144:c2599244-2598951 [Pseudomonas chlororaphis]
ATGGATTACGAGATCCTGCAGACGACCGTCTTTGCCCAATGGCACACCACGCTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCTTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGCGGTCTCTCGGAAATGCGCG
TGAATATGGGAGCCGGCTACCGCATCTATTTCACCGTGCGCGGTAATACCCTCATCGTCCTGCTGCTGGGCGGCGACAAG
TCCACCCAGCCTGCCGATATCTGCCAGGCCCGTTCCCTGGCCAAGGAGTTCTGA

Antitoxin

Protein

• Length: 258 a.a.
• Molecular weight: 28905.25 Da
• Isoelectric Point: 9.7202

>AT222835 WP_044206245.1 NZ_CP086253:c3325004-3324231 [Pectobacterium aquaticum]
MSSKLNWLLQNTAPGSLVLQSWLTKNGISPSLANKYMHSDWLQKLRAGVYVRSGREAQWSDAVLCLQNQLGISVHLAGLT
SLTYQGRSHYLHLKHQAIWLCVEDKASLPKWFKEFPNVEWLLLSNQKLNMNDEKYLTEIEIKGELLKASVPELAAYEIAN
AVPGSLSFEHAAELFQGLVNLSPRKVEVLLQSSRAVQTNRLYLFLADHYAHAWGKRIDKANVELGAGKRQIVSGGKLDQK
YQITVPERFVSKGISHG

Nucleotide

• Length: 774 bp

>AT222835 NZ_CP118144:c2598949-2598659 [Pseudomonas chlororaphis]
ATGTCCGACACCCTGCTTCCCTTCGACATCGCCGCCCTGCTCGACAGCGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGATGAACTGATCCGCGCCCTGGGCCATGTCGCCAGGGCCCGGGGCATGACGCAGATTGCCA
AGGCCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCTTTTGCCCCGGGTGCCAAGCCGCGTTTCGATACCGTGGTCAAG
GTCATGCGCGCGCTGGGCCTGCAGCTGTGCACCACCGTGTCCCGCGGCTGA

Structures

Antitoxin

• AlphaFold DB: A0A3R8N1C1