Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 1686755..1687480 Replicon chromosome
Accession NZ_CP086253
Organism Pectobacterium aquaticum strain A212-S19-A16

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag DMB82_RS07880 Protein ID WP_116162555.1
Coordinates 1687160..1687480 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag DMB82_RS07875 Protein ID WP_116162557.1
Coordinates 1686755..1687090 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DMB82_RS07840 (DMB82_0007880) 1682665..1683396 + 732 WP_116162683.1 DUF3944 domain-containing protein -
DMB82_RS07845 (DMB82_0007885) 1683451..1684128 + 678 WP_116162569.1 WYL domain-containing protein -
DMB82_RS07850 (DMB82_0007890) 1684226..1684591 + 366 WP_116162567.1 hypothetical protein -
DMB82_RS07855 (DMB82_0007895) 1684634..1685041 + 408 WP_116162565.1 hypothetical protein -
DMB82_RS07860 (DMB82_0007900) 1685074..1685286 + 213 WP_116162563.1 hypothetical protein -
DMB82_RS07865 (DMB82_0007905) 1685368..1686189 + 822 WP_116162561.1 DUF932 domain-containing protein -
DMB82_RS07870 (DMB82_0007910) 1686242..1686715 + 474 WP_116162559.1 DNA repair protein RadC -
DMB82_RS07875 (DMB82_0007915) 1686755..1687090 + 336 WP_116162557.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
DMB82_RS07880 (DMB82_0007920) 1687160..1687480 + 321 WP_116162555.1 TA system toxin CbtA family protein Toxin
DMB82_RS07885 (DMB82_0007925) 1687596..1688429 + 834 WP_116162553.1 DUF4942 domain-containing protein -
DMB82_RS07890 (DMB82_0007930) 1688524..1688754 + 231 WP_116162551.1 type II toxin-antitoxin system VapB family antitoxin -
DMB82_RS07895 (DMB82_0007935) 1688754..1689182 + 429 WP_116162549.1 tRNA(fMet)-specific endonuclease VapC -
DMB82_RS07900 (DMB82_0007940) 1689493..1689690 - 198 WP_226888919.1 hypothetical protein -
DMB82_RS07905 (DMB82_0007945) 1689894..1690181 - 288 WP_102118418.1 HigA family addiction module antitoxin -
DMB82_RS07910 (DMB82_0007950) 1690181..1690459 - 279 WP_102118419.1 type II toxin-antitoxin system RelE/ParE family toxin -
DMB82_RS07915 (DMB82_0007955) 1690589..1690969 - 381 WP_208644314.1 hypothetical protein -
DMB82_RS07920 (DMB82_0007960) 1691489..1691626 + 138 WP_240348903.1 YnfU family zinc-binding protein -
DMB82_RS07925 (DMB82_0007965) 1691665..1691856 + 192 WP_116162547.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1656312..1692867 36555


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-106)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12137.87 Da        Isoelectric Point: 4.7768

>T222831 WP_116162555.1 NZ_CP086253:1687160-1687480 [Pectobacterium aquaticum]
MQTTPAIPLREDQSCPPPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGVTLVNAVNFLVERYELVRIDRNGF
NWQEQSPFLSAVDVLRARRATGLLKT

Download         Length: 321 bp

>T222831 NZ_CP118144:780967-781263 [Pseudomonas chlororaphis]
ATGCGTGTAATCACGGCTAAACGAATTTGGGATGCCAAGGAAAAATGGCCACAGTCGGCCAAGGCGTTGGATGATTGGTA
TCGCGCGCTTAAACGCAATCGGCTTGCGGATTTTGCCGCGATGAAGGCGATGTTTCCGGCGGTGGACAAGGTCGGACCGC
TGCATGTGTTCGATATCGGTGGCAACAAGATACGACTGATTGCATTGGTCCGTTATACGACGCAAAAGCTCTATATCCGC
CATGTGTTGGACCACCGTGAATATGACCGGGGTAAGTGGAAGGAGGATCGAGGATGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12491.88 Da        Isoelectric Point: 4.8040

>AT222831 WP_116162557.1 NZ_CP086253:1686755-1687090 [Pectobacterium aquaticum]
MPSSDTPEWGLKRAVTPQFGARLVQEGNYLHYLADRASVVGTFSESEARNLEQSFPELIKQLEQKLRSGELNPRQQGCIT
LHYNEWTCEADTLGSFGYVYISVYPSSTATQ

Download         Length: 336 bp

>AT222831 NZ_CP118144:781260-781661 [Pseudomonas chlororaphis]
ATGAGTGCATTGATCGAGCAAGTGGCCGAACACTGGCAGTTCGTTGCGCCGTTGCTGCGCAAGCCGAAAACCGAGGCGGA
CTACGACAGGCTGGTTCAGGCCCTTGACGAGTTGTTGGACCTGACAGGGGAAGATGAGGCCCATCCTCTCAACAGCCTGG
TGGACATCATCGGGGACTGGATCGAAGCCTACGATCTTGAACATCGCCCGATGCCTGTTGCCAGCGGAATAGATGTGTTG
CGCTACATGATGCGCGAACACGGTCTGACCCAGAGCGACCTGCCCGGTGTCGGCGCGCAGTCGGTAGTCTCGGAGATCCT
GAGCGGCAAGCGTCAGCTCAACCTGCGTCAGATCCGCTGGCTGGCCGAACGTTTCAAGGTCTCGATGGAAACCTTTATCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References