Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
Location | 429069..429853 | Replicon | chromosome |
Accession | NZ_CP086253 | ||
Organism | Pectobacterium aquaticum strain A212-S19-A16 |
Toxin (Protein)
Gene name | TacT2 | Uniprot ID | - |
Locus tag | DMB82_RS01980 | Protein ID | WP_116164350.1 |
Coordinates | 429359..429853 (+) | Length | 165 a.a. |
Antitoxin (Protein)
Gene name | TacA2 | Uniprot ID | A0A3S0Y1Y3 |
Locus tag | DMB82_RS01975 | Protein ID | WP_038921611.1 |
Coordinates | 429069..429362 (+) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DMB82_RS01950 (DMB82_0001960) | 424645..425640 | - | 996 | WP_039539586.1 | LysR family transcriptional regulator | - |
DMB82_RS01955 (DMB82_0001965) | 426194..426529 | - | 336 | WP_102117174.1 | hypothetical protein | - |
DMB82_RS01960 (DMB82_0001970) | 427104..428049 | + | 946 | Protein_376 | IS30 family transposase | - |
DMB82_RS01965 (DMB82_0001975) | 428046..428201 | - | 156 | WP_228400031.1 | hypothetical protein | - |
DMB82_RS01970 (DMB82_0001980) | 428261..428632 | - | 372 | WP_226887596.1 | Arm DNA-binding domain-containing protein | - |
DMB82_RS01975 (DMB82_0001985) | 429069..429362 | + | 294 | WP_038921611.1 | DUF1778 domain-containing protein | Antitoxin |
DMB82_RS01980 (DMB82_0001990) | 429359..429853 | + | 495 | WP_116164350.1 | GNAT family N-acetyltransferase | Toxin |
DMB82_RS01985 (DMB82_0001995) | 430024..430353 | + | 330 | WP_116164352.1 | hypothetical protein | - |
DMB82_RS01990 (DMB82_0002000) | 431112..431327 | + | 216 | Protein_382 | helix-turn-helix domain-containing protein | - |
DMB82_RS01995 (DMB82_0002005) | 432219..433295 | + | 1077 | WP_116164356.1 | hypothetical protein | - |
DMB82_RS02000 (DMB82_0002010) | 433315..434010 | + | 696 | WP_167469176.1 | HAD family hydrolase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 427645..428049 | 404 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 165 a.a. Molecular weight: 17728.56 Da Isoelectric Point: 6.8526
>T222827 WP_116164350.1 NZ_CP086253:429359-429853 [Pectobacterium aquaticum]
MISAPEPLHAEHVLSSFCCGVESTDNWLKLRAMKNQVTGASRTFVSCNDSKVLAYYSLASSAMATNAAPGRFRRNMPDPI
PVVVLGRLAVDTSLHGQGVGRALVRDVGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMMLMVTLGDLVD
SLSI
MISAPEPLHAEHVLSSFCCGVESTDNWLKLRAMKNQVTGASRTFVSCNDSKVLAYYSLASSAMATNAAPGRFRRNMPDPI
PVVVLGRLAVDTSLHGQGVGRALVRDVGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMMLMVTLGDLVD
SLSI
Download Length: 495 bp
>T222827 NZ_CP118143:c6350679-6350380 [Pseudomonas chlororaphis]
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATTGC
TGCGCGGATTTTTCGCCTGGCCAACGGTCTTGCCGGGGACGTGTCGCCGGTGGGCGAAGGCGTCAGTGAGCTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCAGCGCGGCTTGCAACTCGTCATCCTGTTGTGCGGCGGCGACAAGAGT
CGCCAGGGCCGCGATATCGAACTGGCCAAACAGCTGGCCCGTCGTTGGAGCCGATCATGA
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATTGC
TGCGCGGATTTTTCGCCTGGCCAACGGTCTTGCCGGGGACGTGTCGCCGGTGGGCGAAGGCGTCAGTGAGCTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCAGCGCGGCTTGCAACTCGTCATCCTGTTGTGCGGCGGCGACAAGAGT
CGCCAGGGCCGCGATATCGAACTGGCCAAACAGCTGGCCCGTCGTTGGAGCCGATCATGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10824.38 Da Isoelectric Point: 10.1968
>AT222827 WP_038921611.1 NZ_CP086253:429069-429362 [Pectobacterium aquaticum]
VPATNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLARLDQAPAPN
AALRKTMQTPAPWEQKK
VPATNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLARLDQAPAPN
AALRKTMQTPAPWEQKK
Download Length: 294 bp
>AT222827 NZ_CP118143:c6350383-6350090 [Pseudomonas chlororaphis]
ATGAACGAACCGCTTTTCGACTATGACCCCGCCACGGCCCTGCGCGACCCGCAGGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCATTCAGCGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGTGCACTGGGGCTGGACATGACGGCGCGGGTGCATGGGGCGTCTTGA
ATGAACGAACCGCTTTTCGACTATGACCCCGCCACGGCCCTGCGCGACCCGCAGGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCATTCAGCGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGTGCACTGGGGCTGGACATGACGGCGCGGGTGCATGGGGCGTCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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