222825

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 337234..337765 Replicon chromosome
Accession NZ_CP086253
Organism Pectobacterium aquaticum strain A212-S19-A16

Toxin (Protein)


Gene name stbE Uniprot ID A0A249QBN7
Locus tag DMB82_RS01555 Protein ID WP_039493031.1
Coordinates 337478..337765 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A3R8PFZ6
Locus tag DMB82_RS01550 Protein ID WP_039470361.1
Coordinates 337234..337488 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DMB82_RS01525 (DMB82_0001530) 332713..333303 - 591 WP_005975525.1 DnaA initiator-associating protein DiaA -
DMB82_RS01530 (DMB82_0001535) 333345..333701 - 357 WP_116156379.1 YraN family protein -
DMB82_RS01535 (DMB82_0001540) 333698..335716 - 2019 WP_116163554.1 penicillin-binding protein activator -
DMB82_RS01540 (DMB82_0001545) 335778..336665 + 888 WP_116163556.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
DMB82_RS01550 (DMB82_0001555) 337234..337488 + 255 WP_039470361.1 plasmid stabilization protein Antitoxin
DMB82_RS01555 (DMB82_0001560) 337478..337765 + 288 WP_039493031.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DMB82_RS01560 (DMB82_0001565) 337941..338726 + 786 WP_102117107.1 4,5-DOPA dioxygenase extradiol -
DMB82_RS01565 (DMB82_0001570) 338988..340148 - 1161 WP_102117109.1 glutathionylspermidine synthase family protein -
DMB82_RS01570 (DMB82_0001575) 340159..340833 - 675 WP_102117110.1 DUF1190 family protein -
DMB82_RS01575 (DMB82_0001580) 341104..342498 - 1395 WP_116163558.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10993.93 Da        Isoelectric Point: 10.7694

>T222825 WP_039493031.1 NZ_CP086253:337478-337765 [Pectobacterium aquaticum]
MTYKLKFVPSALKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA

Download         Length: 288 bp

>T222825 NZ_CP118143:c2599505-2599212 [Pseudomonas chlororaphis]
ATGGATTACGAGATCCTGCAGACGACCGTCTTTGCCCAATGGCACACCACGCTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCTTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGCGGTCTCTCGGAAATGCGCG
TGAATATGGGAGCCGGCTACCGCATCTATTTCACCGTGCGCGGTAATACCCTCATCGTCCTGCTGCTGGGCGGCGACAAG
TCCACCCAGCCTGCCGATATCTGCCAGGCCCGTTCCCTGGCCAAGGAGTTCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9192.34 Da        Isoelectric Point: 3.7947

>AT222825 WP_039470361.1 NZ_CP086253:337234-337488 [Pectobacterium aquaticum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
PDDL

Download         Length: 255 bp

>AT222825 NZ_CP118143:c2599210-2598920 [Pseudomonas chlororaphis]
ATGTCCGACACCCTGCTTCCCTTCGACATCGCCGCCCTGCTCGACAGCGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGATGAACTGATCCGCGCCCTGGGCCATGTCGCCAGGGCCCGGGGCATGACGCAGATTGCCA
AGGCCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCTTTTGCCCCGGGTGCCAAGCCGCGTTTCGATACCGTGGTCAAG
GTCATGCGCGCGCTGGGCCTGCAGCTGTGCACCACCGTGTCCCGCGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A249QBN7

Antitoxin

Source ID Structure
AlphaFold DB A0A3R8PFZ6

References