Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2580973..2581118 | Replicon | chromosome |
| Accession | NC_009648 | ||
| Organism | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2580980..2581082 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2580973..2581118 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KPN_RS12680 (KPN_02351) | 2576506..2577939 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| KPN_RS12685 (KPN_02352) | 2578055..2578294 | + | 240 | WP_002911393.1 | YebV family protein | - |
| KPN_RS12690 (KPN_02353) | 2578392..2578583 | + | 192 | WP_002911395.1 | YebW family protein | - |
| KPN_RS12695 (KPN_02354) | 2578580..2579233 | - | 654 | WP_004891053.1 | protein-serine/threonine phosphatase | - |
| KPN_RS12700 (KPN_02355) | 2579390..2580358 | + | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| KPN_RS30490 | 2580463..2580606 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 2580973..2581118 | + | 146 | - | - | Antitoxin |
| - | 2580980..2581082 | - | 103 | - | - | Toxin |
| KPN_RS12710 (KPN_02356) | 2581241..2581579 | - | 339 | WP_002911404.1 | YebY family protein | - |
| KPN_RS12715 (KPN_02357) | 2581596..2582465 | - | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| KPN_RS12720 (KPN_02358) | 2582469..2582843 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| KPN_RS12725 (KPN_02359) | 2582956..2583186 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| KPN_RS12730 (KPN_02360) | 2583265..2583924 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| KPN_RS12735 (KPN_02361) | 2583928..2585988 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T22281 NC_009648:c2581082-2580980 [Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT22281 NC_009648:2580973-2581118 [Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT