Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2580973..2581118 Replicon chromosome
Accession NC_009648
Organism Klebsiella pneumoniae subsp. pneumoniae MGH 78578

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2580980..2581082 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2580973..2581118 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KPN_RS12680 (KPN_02351) 2576506..2577939 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KPN_RS12685 (KPN_02352) 2578055..2578294 + 240 WP_002911393.1 YebV family protein -
KPN_RS12690 (KPN_02353) 2578392..2578583 + 192 WP_002911395.1 YebW family protein -
KPN_RS12695 (KPN_02354) 2578580..2579233 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
KPN_RS12700 (KPN_02355) 2579390..2580358 + 969 WP_004151446.1 VirK/YbjX family protein -
KPN_RS30490 2580463..2580606 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2580973..2581118 + 146 - - Antitoxin
- 2580980..2581082 - 103 - - Toxin
KPN_RS12710 (KPN_02356) 2581241..2581579 - 339 WP_002911404.1 YebY family protein -
KPN_RS12715 (KPN_02357) 2581596..2582465 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
KPN_RS12720 (KPN_02358) 2582469..2582843 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KPN_RS12725 (KPN_02359) 2582956..2583186 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KPN_RS12730 (KPN_02360) 2583265..2583924 + 660 WP_002911407.1 exodeoxyribonuclease X -
KPN_RS12735 (KPN_02361) 2583928..2585988 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T22281 NC_009648:c2581082-2580980 [Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT22281 NC_009648:2580973-2581118 [Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References