Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/- |
Location | 4069586..4070807 | Replicon | chromosome |
Accession | NZ_CP086213 | ||
Organism | Pseudomonas aeruginosa strain Pa3 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | A0A0H2Z8V4 |
Locus tag | LLJ53_RS19150 | Protein ID | WP_003110488.1 |
Coordinates | 4070229..4070807 (+) | Length | 193 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | LLJ53_RS19145 | Protein ID | WP_003088112.1 |
Coordinates | 4069586..4070140 (+) | Length | 185 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LLJ53_RS19120 (LLJ53_19120) | 4065154..4065705 | + | 552 | WP_003450159.1 | XRE family transcriptional regulator | - |
LLJ53_RS19125 (LLJ53_19125) | 4065702..4066100 | - | 399 | WP_003088123.1 | NADH-quinone oxidoreductase subunit A | - |
LLJ53_RS19130 (LLJ53_19130) | 4066113..4066436 | - | 324 | WP_015648646.1 | multidrug efflux SMR transporter | - |
LLJ53_RS19135 (LLJ53_19135) | 4066767..4067228 | + | 462 | WP_003102736.1 | (2Fe-2S)-binding protein | - |
LLJ53_RS19140 (LLJ53_19140) | 4067233..4069428 | + | 2196 | WP_003122807.1 | xanthine dehydrogenase family protein molybdopterin-binding subunit | - |
LLJ53_RS19145 (LLJ53_19145) | 4069586..4070140 | + | 555 | WP_003088112.1 | helix-turn-helix transcriptional regulator | Antitoxin |
LLJ53_RS19150 (LLJ53_19150) | 4070229..4070807 | + | 579 | WP_003110488.1 | HD domain-containing protein | Toxin |
LLJ53_RS19155 (LLJ53_19155) | 4070916..4072103 | - | 1188 | WP_003102741.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
LLJ53_RS19160 (LLJ53_19160) | 4072093..4074264 | - | 2172 | WP_025297367.1 | type I secretion system permease/ATPase | - |
LLJ53_RS19165 (LLJ53_19165) | 4074254..4075531 | - | 1278 | WP_003102743.1 | TolC family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 193 a.a. Molecular weight: 21913.75 Da Isoelectric Point: 5.3655
>T222755 WP_003110488.1 NZ_CP086213:4070229-4070807 [Pseudomonas aeruginosa]
MSLELLSNRLEFLREAERLKDVLRSAHTSSGRPESTAEHSWRLCLMALAFEDQLAGLDLGKVLRMCVVHDLGEAIHGDIP
AVEQAAHPDKGEQERADLLQLTRHLDTPLRDRLLALWDEYERGETAEALAVKALDKLETLLQHTQGDNPADFDYAFNLDY
GRRYTDRAPLFKTLRELLDARTRQRLAARRDA
MSLELLSNRLEFLREAERLKDVLRSAHTSSGRPESTAEHSWRLCLMALAFEDQLAGLDLGKVLRMCVVHDLGEAIHGDIP
AVEQAAHPDKGEQERADLLQLTRHLDTPLRDRLLALWDEYERGETAEALAVKALDKLETLLQHTQGDNPADFDYAFNLDY
GRRYTDRAPLFKTLRELLDARTRQRLAARRDA
Download Length: 579 bp
>T222755 NZ_CP118135:c1753779-1753483 [Pseudomonas chlororaphis]
ATGCATATCATCACCGCCAAACGAATCTGGGAGGCCAAGAACCGCTGGCCACAATCGGCCAATGCTCTGGAAACCTGGTA
CAGAAAAGCCAAAAGCCTCAATCCGGCCGATTTTGCAGCCATCAAGGCGGTATTTCCGGCCACCGACAAAGTGGGGGCGT
TTCACGTCTTCGATATTGGTGGCAACAAGTTACGAATCATCGCCGTGGTGCGTTATGAAGTACGACGTCTCTATATCAGG
CACGTGCTGGACCATCACGAATACGACAAAGGCAGGTGGAAGGAGGAAACCAGATGA
ATGCATATCATCACCGCCAAACGAATCTGGGAGGCCAAGAACCGCTGGCCACAATCGGCCAATGCTCTGGAAACCTGGTA
CAGAAAAGCCAAAAGCCTCAATCCGGCCGATTTTGCAGCCATCAAGGCGGTATTTCCGGCCACCGACAAAGTGGGGGCGT
TTCACGTCTTCGATATTGGTGGCAACAAGTTACGAATCATCGCCGTGGTGCGTTATGAAGTACGACGTCTCTATATCAGG
CACGTGCTGGACCATCACGAATACGACAAAGGCAGGTGGAAGGAGGAAACCAGATGA
Antitoxin
Download Length: 185 a.a. Molecular weight: 20454.63 Da Isoelectric Point: 8.1590
>AT222755 WP_003088112.1 NZ_CP086213:4069586-4070140 [Pseudomonas aeruginosa]
MTEPLPSSSLGPALRRWRLLHRVKQTHAAELLGVAQSTISRWESGTQALLVEERARLERLLGARLEAAADQALARLVEAN
PQPVHLICDLTHRLLACSPARAAQFGVPLGELLDRSLWPYCSEEILRQEATLEELGWRELLAPPALEFASGANASAIVPI
RRSRCRWTRMTLSDGRAVRLVETL
MTEPLPSSSLGPALRRWRLLHRVKQTHAAELLGVAQSTISRWESGTQALLVEERARLERLLGARLEAAADQALARLVEAN
PQPVHLICDLTHRLLACSPARAAQFGVPLGELLDRSLWPYCSEEILRQEATLEELGWRELLAPPALEFASGANASAIVPI
RRSRCRWTRMTLSDGRAVRLVETL
Download Length: 555 bp
>AT222755 NZ_CP118135:c1753486-1753085 [Pseudomonas chlororaphis]
ATGAACGTTCTGGTGAAGCAGGCGGCGGATCATTGGCATTTCGTGGCGCCTGTGTTGCGTAAACCCAAGACCGAAGCCGA
TTACGATGCATTGGTCGCCGCGCTGGATGAACTGCTGGATCTCATGGGAGAGGACGAGAACCATCCAGTGACTTCGCTGG
TGGACATCATCGGCGACTGGATCGAAGCCTACGACGAAGAACACCGACCGATGCCGATAGCCAGTGGTGTTGACGTCTTG
CGCTCCCTGATGCGCGAACATGGCCTGACCCAGAGCGATCTGCCAGGCGTGGGCGCGCAGTCGGTGGTTTCCGAAGTGCT
GAGCGGCAAGCGCCAGCTCAACCTGCGGCAGATCCGCTGGCTGGCCGAGCGCTTCGGTGTTTCGGCCGAGGTCTTTATCT
GA
ATGAACGTTCTGGTGAAGCAGGCGGCGGATCATTGGCATTTCGTGGCGCCTGTGTTGCGTAAACCCAAGACCGAAGCCGA
TTACGATGCATTGGTCGCCGCGCTGGATGAACTGCTGGATCTCATGGGAGAGGACGAGAACCATCCAGTGACTTCGCTGG
TGGACATCATCGGCGACTGGATCGAAGCCTACGACGAAGAACACCGACCGATGCCGATAGCCAGTGGTGTTGACGTCTTG
CGCTCCCTGATGCGCGAACATGGCCTGACCCAGAGCGATCTGCCAGGCGTGGGCGCGCAGTCGGTGGTTTCCGAAGTGCT
GAGCGGCAAGCGCCAGCTCAACCTGCGGCAGATCCGCTGGCTGGCCGAGCGCTTCGGTGTTTCGGCCGAGGTCTTTATCT
GA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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