Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 4651706..4653225 Replicon chromosome
Accession NZ_CP086200
Organism Xanthomonas oryzae pv. oryzae strain GXO2006

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag LLC55_RS21920 Protein ID WP_011259680.1
Coordinates 4652302..4653225 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag LLC55_RS21915 Protein ID WP_011409027.1
Coordinates 4651706..4652305 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LLC55_RS21875 (LLC55_21895) 4647388..4647924 - 537 WP_011409032.1 lipocalin family protein -
LLC55_RS21885 (LLC55_21905) 4648194..4648661 - 468 WP_181718264.1 hypothetical protein -
LLC55_RS21890 (LLC55_21910) 4648642..4648932 - 291 WP_011409031.1 hypothetical protein -
LLC55_RS21900 (LLC55_21920) 4649431..4650462 + 1032 WP_042465093.1 IS630 family transposase -
LLC55_RS21905 (LLC55_21925) 4650444..4651019 - 576 WP_011409029.1 BrxE family protein -
LLC55_RS21910 (LLC55_21930) 4651051..4651341 - 291 WP_228329665.1 FaeA/PapI family transcriptional regulator -
LLC55_RS21915 (LLC55_21935) 4651706..4652305 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LLC55_RS21920 (LLC55_21940) 4652302..4653225 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LLC55_RS21925 (LLC55_21945) 4653305..4653775 - 471 WP_228329666.1 helix-turn-helix domain-containing protein -
LLC55_RS21930 (LLC55_21950) 4654241..4654483 + 243 WP_011409025.1 hypothetical protein -
LLC55_RS21935 (LLC55_21955) 4654935..4655900 - 966 Protein_4203 IS1595-like element ISXo5 family transposase -
LLC55_RS21940 (LLC55_21960) 4655995..4656483 + 489 WP_011409022.1 hypothetical protein -
LLC55_RS21945 (LLC55_21965) 4656500..4657032 - 533 Protein_4205 methyltransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T222724 WP_011259680.1 NZ_CP086200:4652302-4653225 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T222724 NZ_CP118060:835661-835867 [Staphylococcus haemolyticus]
ATGAACTTTAGTGAAATTAGAATTAGTGAATTAAATACTGAAGAGCAAGCTAATTCGCTCCAACATAGACTTGAGAAGAT
GATAGGTGTAGATGAAGTAATTGTAGAACTAAATGACCAATTAGTTAAAATTTCTTATGAAACACCAACGAATTTAAATA
GTATTGAAAAAGAAATTTATGATGATGGTTATAAGGTATTAGGTTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT222724 WP_011409027.1 NZ_CP086200:4651706-4652305 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT222724 NZ_CP118060:835356-835649 [Staphylococcus haemolyticus]
TTGAATAATCATGAAAATGCACATCATTCCGAGCAAATTAAAATGAATTTAAAATCAAGACTAAATCGTATTGAAGGGCA
AGTTAGAGCGATTAATCGCATGATTGAAGAAGATGTATACTGTGATGACGTGCTAACTCAAATTAGAGCTACAAGATCTG
CATTAAATAGTGTGGCCACTAAGTTGCTAGATCATCATATGAAAAGCTGTATCATGGATAAAGTGAATAACGGCGCTCAA
GAAGAAGCGATGGAAGAATTGTTAGTGACATTTCAAAAATTAATGAAAGATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References