Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1073438..1074183 Replicon chromosome
Accession NZ_CP086200
Organism Xanthomonas oryzae pv. oryzae strain GXO2006

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag LLC55_RS05160 Protein ID WP_199285672.1
Coordinates 1073854..1074183 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag LLC55_RS05155 Protein ID WP_011407754.1
Coordinates 1073438..1073857 (-) Length 140 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LLC55_RS05135 (LLC55_05135) 1069726..1070052 - 327 Protein_974 hypothetical protein -
LLC55_RS05140 (LLC55_05140) 1070354..1071589 + 1236 WP_011257570.1 ISL3-like element ISXoo13 family transposase -
LLC55_RS05145 (LLC55_05145) 1071627..1072283 - 657 WP_075246166.1 phosphate phosphatase -
LLC55_RS05150 (LLC55_05150) 1072418..1073386 - 969 WP_011258802.1 IS5-like element ISXo1 family transposase -
LLC55_RS05155 (LLC55_05155) 1073438..1073857 - 420 WP_011407754.1 macro domain-containing protein Antitoxin
LLC55_RS05160 (LLC55_05160) 1073854..1074183 - 330 WP_199285672.1 DUF4433 domain-containing protein Toxin
LLC55_RS05165 (LLC55_05165) 1074286..1075605 + 1320 WP_011407756.1 IS701 family transposase -
LLC55_RS05170 (LLC55_05170) 1075649..1075984 - 336 WP_011407757.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
LLC55_RS05175 (LLC55_05175) 1076316..1077242 - 927 WP_011257932.1 Grx4 family monothiol glutaredoxin -
LLC55_RS05180 (LLC55_05180) 1077288..1078079 + 792 WP_011407758.1 polysaccharide deacetylase family protein -
LLC55_RS05190 (LLC55_05190) 1078381..1079052 - 672 WP_011407759.1 class I SAM-dependent methyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 1070354..1075605 5251


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-108)

Antitoxin

(18-130)


Sequences


Toxin        


Download         Length: 110 a.a.        Molecular weight: 13145.86 Da        Isoelectric Point: 7.1160

>T222721 WP_199285672.1 NZ_CP086200:c1074183-1073854 [Xanthomonas oryzae pv. oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Download         Length: 330 bp

>T222721 NZ_CP118050:2798369-2798629 [Lacticaseibacillus rhamnosus]
ATGATTAAAACCTGGACCGATGATGCTTGGGCGGACTACATGTATTGGCATGATCAAAACGACAAGCGGACAATCAAACG
AATTAATCAACTCATTCAAGCCATTGACCGTGACCCTTATAAAGGCATCGGAAAACCTGAGCCACTTAGATATGCGCTAA
CCGGAAAATGGTCACGTCGGATTGATCAGGAAAATCGCATCATCTACAGCATTGAAAAGAACCACATTAATATTTTCGCC
TGCCGCACTCACTACAGTTAA

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15607.02 Da        Isoelectric Point: 6.4733

>AT222721 WP_011407754.1 NZ_CP086200:c1073857-1073438 [Xanthomonas oryzae pv. oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Download         Length: 420 bp

>AT222721 NZ_CP118050:2798107-2798376 [Lacticaseibacillus rhamnosus]
ATGGAAGCAACGAATTATAGTGATTTCCGCCGCAACCTTAAGCATTATATGAGTCAAGTCAACGAAGACGCCGAACCGCT
ACTGGTTACCGCTAAAGATGATGATGACAATGTGGTGGTTATGAGCAAGCACGATTTTGACGCCATCGAAGAAACCCTGT
ATTTACTCAGCAATCCCAAGCTGATGGCCAAAATCAAACGTGGTGATGCCCAAATTGCCGCTGGAAAGGCTAAACAGCAC
GAGTTGTTAACGGACTTCGATCATGATTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References