222720

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 423878..424228 Replicon chromosome
Accession NZ_CP086200
Organism Xanthomonas oryzae pv. oryzae strain GXO2006

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag LLC55_RS02010 Protein ID WP_011257368.1
Coordinates 424094..424228 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag LLC55_RS02005 Protein ID WP_011407410.1
Coordinates 423878..424030 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LLC55_RS01980 (LLC55_01980) 420158..420841 - 684 WP_011257363.1 dTMP kinase -
LLC55_RS01985 (LLC55_01985) 421321..421863 - 543 Protein_380 GTPase -
LLC55_RS01990 (LLC55_01990) 421860..422315 - 456 Protein_381 hypothetical protein -
LLC55_RS01995 (LLC55_01995) 422307..422525 - 219 Protein_382 hypothetical protein -
LLC55_RS02000 (LLC55_02000) 422847..423770 + 924 WP_011407409.1 arginase -
LLC55_RS02005 (LLC55_02005) 423878..424030 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
LLC55_RS02010 (LLC55_02010) 424094..424228 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
LLC55_RS02015 (LLC55_02015) 424469..424678 + 210 WP_011407411.1 CsbD family protein -
LLC55_RS02020 (LLC55_02020) 424847..426136 + 1290 WP_075242213.1 tryptophan--tRNA ligase -
LLC55_RS02025 (LLC55_02025) 426267..427211 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T222720 WP_011257368.1 NZ_CP086200:424094-424228 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T222720 NZ_CP118050:c2536497-2536114 [Lacticaseibacillus rhamnosus]
ATGGATGTAACAGTCAAACGCGGGGATGTATTTTTCGCCGATTTATCGCCGGTTGTCGGGTCGGAACAAGGCGGCAACCG
GCCCGTACTTATTATTCAAAACAATGTTGGTAACCATTATAGCCCCACTGTTATCGTGGCTGCCATTACCTCCAAAATCC
AAAAACCCAAAATGCCCACCCATGTCGGTTTGCGCGCCAAGCAAGACGGGGTTGAGCGTAATTCAGTCATTTTGCTTGAA
CAGATTCGTACAATTGATAAGCAACGGTTACAGGCACGCGTTACCGCTCTTTCAAGTGCCAAAATGGCAGCGGTGGATCG
GGCACTGGCGATATCGGTCGGACTCGTCAGCTTGCCTAAGCCGAAAACATATAATAAAAACTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT222720 WP_011407410.1 NZ_CP086200:423878-424030 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT222720 NZ_CP118050:c2536765-2536517 [Lacticaseibacillus rhamnosus]
ATGAAGAAGGAAACGTCAGTAACGGTCGCGCTTGATAGTGCTATCAAAGCGCGTTTGGATGCCTATTGCGAGTTGAATGA
TATGGGTGTTCAGGATGTCATTACTGAAGCAGTGGCGAAGTTTTTGCAGTCACAAGCACCTGAGATCAATCAATTGATTT
CTGGCTATGTGGCAATGGGACAAATCAATACGGAAATCAGCCATGCTTTCTCCGCCTGCGAAAGTGAGGCATACGCCCAT
ATTCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References