222714

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 3908379..3908729 Replicon chromosome
Accession NZ_CP086197
Organism Xanthomonas oryzae strain JS97-2

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag LL929_RS18335 Protein ID WP_011257368.1
Coordinates 3908379..3908513 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag LL929_RS18340 Protein ID WP_011407410.1
Coordinates 3908577..3908729 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL929_RS18320 (LL929_18295) 3905393..3906337 - 945 WP_041181936.1 MBL fold metallo-hydrolase -
LL929_RS18325 (LL929_18300) 3906468..3907757 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
LL929_RS18330 (LL929_18305) 3907926..3908135 - 210 WP_011407411.1 CsbD family protein -
LL929_RS18335 (LL929_18310) 3908379..3908513 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
LL929_RS18340 (LL929_18315) 3908577..3908729 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
LL929_RS18345 (LL929_18320) 3908837..3909760 - 924 WP_011407409.1 arginase -
LL929_RS18350 (LL929_18325) 3910082..3910300 + 219 Protein_3499 hypothetical protein -
LL929_RS18355 (LL929_18330) 3910292..3910756 + 465 Protein_3500 hypothetical protein -
LL929_RS18360 (LL929_18335) 3910753..3911295 + 543 Protein_3501 GTPase -
LL929_RS18365 (LL929_18340) 3911775..3912458 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T222714 WP_011257368.1 NZ_CP086197:c3908513-3908379 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T222714 NZ_CP118048:c295995-295900 [Enterococcus faecalis]
ATGTACGAGATTGTCACAAAAATTCTTGTGCCGATTTTTGTCGGGATTGTCCTGAAACTTGTAACCATTTGGTTGGAAAA
ACAGAACGAGGAATAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT222714 WP_011407410.1 NZ_CP086197:c3908729-3908577 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT222714 NZ_CP118048:295801-295865 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGCGGTAGGGTGTCTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References