Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 989304..990823 Replicon chromosome
Accession NZ_CP086197
Organism Xanthomonas oryzae strain JS97-2

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag LL929_RS04805 Protein ID WP_011259680.1
Coordinates 989900..990823 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag LL929_RS04800 Protein ID WP_011409027.1
Coordinates 989304..989903 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL929_RS04765 (LL929_04760) 984986..985522 - 537 WP_011409032.1 lipocalin family protein -
LL929_RS04775 (LL929_04770) 985792..986259 - 468 WP_181718264.1 hypothetical protein -
LL929_RS04780 (LL929_04775) 986240..986530 - 291 WP_011409031.1 hypothetical protein -
LL929_RS04785 (LL929_04780) 987029..988060 + 1032 WP_042465093.1 IS630 family transposase -
LL929_RS04790 (LL929_04785) 988042..988617 - 576 WP_011409029.1 BrxE family protein -
LL929_RS04795 (LL929_04790) 988649..988921 - 273 WP_241847193.1 FaeA/PapI family transcriptional regulator -
LL929_RS04800 (LL929_04795) 989304..989903 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LL929_RS04805 (LL929_04800) 989900..990823 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LL929_RS04810 (LL929_04805) 990903..991373 - 471 WP_228383551.1 helix-turn-helix domain-containing protein -
LL929_RS04815 (LL929_04810) 991839..992081 + 243 WP_011409025.1 hypothetical protein -
LL929_RS04820 (LL929_04815) 992533..993498 - 966 Protein_916 IS1595-like element ISXo5 family transposase -
LL929_RS04825 (LL929_04820) 993593..994081 + 489 WP_011409022.1 hypothetical protein -
LL929_RS04830 (LL929_04825) 994098..994630 - 533 Protein_918 methyltransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T222711 WP_011259680.1 NZ_CP086197:989900-990823 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T222711 NZ_CP118044:c2414529-2414263 [Staphylococcus aureus]
ATGAGCAATTACACGGTTAAGATTAAAAATTCGGCGAAGTTAGATTTAAAGAAAATAAAACATCCTTATTTAAAGAAGAC
ATTTATAGAAATTGTTGAGACTTTAAAAAATAATCCTTATAAAATAACACAATCCTTTGAAAAATTAGAACCTAAATATT
TAGAGCGATATTCAAGAAGAATTAACCTTCAGCACAGGGTCGTCTATACCATAGATGATCGAAATAAAGTAGTATTAATA
CTATCGGCATGGTCACATTATGATTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT222711 WP_011409027.1 NZ_CP086197:989304-989903 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT222711 NZ_CP118044:c2414786-2414529 [Staphylococcus aureus]
ATGATTATCACTAGCCCTACAGAAGCGAGAAAAGATTTTTATCAATTACTAAAAAATGTTAATAATAATCACGAACCAAT
TTATATTAGTGGTAATAATGCCGAAAATAATGCTGTGATTATAGGTTTAGAAGATTGGAAAAGTATACAAGAGACAATGT
ATCTTGTATCTACTGGTACAATGGACAAAGTAAGAGAAAGAGAAAAAGATAATAGTGGTACAACAAATATAGATGATATT
GATTGGGATAATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References