Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3832388..3833133 Replicon chromosome
Accession NZ_CP086196
Organism Xanthomonas oryzae strain KS6-6

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag LL923_RS17985 Protein ID WP_199285672.1
Coordinates 3832804..3833133 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag LL923_RS17980 Protein ID WP_011407754.1
Coordinates 3832388..3832807 (-) Length 140 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL923_RS17960 (LL923_17945) 3828678..3829004 - 327 Protein_3426 hypothetical protein -
LL923_RS17965 (LL923_17950) 3829306..3830540 + 1235 Protein_3427 ISL3 family transposase -
LL923_RS17970 (LL923_17955) 3830578..3831216 - 639 WP_011407753.1 phosphate phosphatase -
LL923_RS17980 (LL923_17965) 3832388..3832807 - 420 WP_011407754.1 macro domain-containing protein Antitoxin
LL923_RS17985 (LL923_17970) 3832804..3833133 - 330 WP_199285672.1 DUF4433 domain-containing protein Toxin
LL923_RS17990 (LL923_17975) 3833236..3834552 + 1317 WP_274394030.1 IS701 family transposase -
LL923_RS17995 (LL923_17980) 3834596..3834931 - 336 WP_011407757.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
LL923_RS18000 (LL923_17985) 3835280..3836206 - 927 WP_011257932.1 Grx4 family monothiol glutaredoxin -
LL923_RS18005 (LL923_17990) 3836252..3837043 + 792 WP_011407758.1 polysaccharide deacetylase family protein -
LL923_RS18015 (LL923_18000) 3837345..3838016 - 672 WP_011407759.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 3829306..3834552 5246


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(3-108)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 13145.86 Da        Isoelectric Point: 7.1160

>T222710 WP_199285672.1 NZ_CP086196:c3833133-3832804 [Xanthomonas oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Download         Length: 330 bp

>T222710 NZ_CP118044:c2356455-2356189 [Staphylococcus aureus]
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15607.02 Da        Isoelectric Point: 6.4733

>AT222710 WP_011407754.1 NZ_CP086196:c3832807-3832388 [Xanthomonas oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Download         Length: 420 bp

>AT222710 NZ_CP118044:c2356706-2356455 [Staphylococcus aureus]
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGATATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References