222709

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3183665..3184015 Replicon chromosome
Accession NZ_CP086196
Organism Xanthomonas oryzae strain KS6-6

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag LL923_RS14830 Protein ID WP_011257368.1
Coordinates 3183881..3184015 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag LL923_RS14825 Protein ID WP_011407410.1
Coordinates 3183665..3183817 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL923_RS14800 (LL923_14785) 3179936..3180619 - 684 WP_011257363.1 dTMP kinase -
LL923_RS14805 (LL923_14790) 3181099..3181641 - 543 Protein_2833 GTPase -
LL923_RS14810 (LL923_14795) 3181638..3182102 - 465 Protein_2834 hypothetical protein -
LL923_RS14815 (LL923_14800) 3182094..3182312 - 219 Protein_2835 hypothetical protein -
LL923_RS14820 (LL923_14805) 3182634..3183557 + 924 WP_011407409.1 arginase -
LL923_RS14825 (LL923_14810) 3183665..3183817 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
LL923_RS14830 (LL923_14815) 3183881..3184015 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
LL923_RS14835 (LL923_14820) 3184259..3184468 + 210 WP_011407411.1 CsbD family protein -
LL923_RS14840 (LL923_14825) 3184637..3185926 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
LL923_RS14845 (LL923_14830) 3186057..3187001 + 945 WP_041181936.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T222709 WP_011257368.1 NZ_CP086196:3183881-3184015 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T222709 NZ_CP118044:c2043486-2043277 [Staphylococcus aureus]
ATGATACATCAAAATACGATTTACACAGCGGGAATTGAAACAGAAGAACAAGTAAGTCAATTGACAGAACGCATTTCAAA
TATGATAGGTGTTCATCAAGTGAATATTAATATAATAGATGGTCAAGTAACTGTATCGTATGAGACACCAGCAAATTTGA
ATAGTATTGAAAAAGAAATCTATGATGAAGGATACAAAATTGTATTTTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT222709 WP_011407410.1 NZ_CP086196:3183665-3183817 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT222709 NZ_CP118044:c2043791-2043498 [Staphylococcus aureus]
ATGACTGAACAAGATAATGCACATCATTCTGAACAAATAAAAACGAATCTTAAATCACGTTTAAATCGAATTGAAGGACA
AGTGAGAGCGATTAATCGCATGATTGAAGAAGATGTCTATTGTGATGATGTCCTTACGCAAATAAGAGCGACACGTTCGG
CGTTAAACAGTGTTGCGATAAAGTTATTAGAACAACATATGAAAAGTTGTATTATGAATAAAGTTAATCAAGGTGCTCAG
GAAGAGGCAATGGAAGAGTTATTAGTGACTTTTCAAAAATTGATTAAAGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References