Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3457175..3458694 Replicon chromosome
Accession NZ_CP086195
Organism Xanthomonas oryzae strain JS158-2

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag LL925_RS16125 Protein ID WP_011259680.1
Coordinates 3457175..3458098 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag LL925_RS16130 Protein ID WP_011409027.1
Coordinates 3458095..3458694 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL925_RS16100 (LL925_16095) 3453368..3453900 + 533 Protein_3078 methyltransferase domain-containing protein -
LL925_RS16105 (LL925_16100) 3453917..3454405 - 489 WP_011409022.1 hypothetical protein -
LL925_RS16110 (LL925_16105) 3454500..3455465 + 966 Protein_3080 IS1595-like element ISXo5 family transposase -
LL925_RS16115 (LL925_16110) 3455917..3456159 - 243 WP_011409025.1 hypothetical protein -
LL925_RS16120 (LL925_16115) 3456625..3457095 + 471 WP_228383551.1 helix-turn-helix domain-containing protein -
LL925_RS16125 (LL925_16120) 3457175..3458098 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LL925_RS16130 (LL925_16125) 3458095..3458694 - 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LL925_RS16135 (LL925_16130) 3459059..3459349 + 291 WP_228329665.1 FaeA/PapI family transcriptional regulator -
LL925_RS16140 (LL925_16135) 3459381..3459956 + 576 WP_011409029.1 BrxE family protein -
LL925_RS16145 (LL925_16140) 3459938..3460969 - 1032 WP_042465093.1 IS630 family transposase -
LL925_RS16150 (LL925_16145) 3461468..3461758 + 291 WP_011409031.1 hypothetical protein -
LL925_RS16155 (LL925_16150) 3461739..3462206 + 468 WP_181718264.1 hypothetical protein -
LL925_RS16165 (LL925_16160) 3462476..3463012 + 537 WP_011409032.1 lipocalin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T222704 WP_011259680.1 NZ_CP086195:c3458098-3457175 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T222704 NZ_CP118043:686024-686812 [Streptococcus agalactiae]
ATGAGATTGGAAGAATTTAGTGAGGTAGAGTTTCAGAAGGCCTTACAGCGAACCATTCGGGCCTTAACCCGAGGAAAGAC
GATTCCAGATCAACCGAAAGCTATTTTGCTTGGTGGACAAAGCGGAGCAGGTAAGACGACTATTCATCGTATCAAGCAAA
AGGAATTTCAAGGTAATATCATTATTATCGATGGTGACAGCTACCGTTCTCAGCATCCCAATTACTTAGCCCTGCAAGAA
AAGTATGGCAAGGATAGCGTGGACTATACCAAGGGATTTGCAGGAAAAATGGTAGAACAGTTGGTTGATGAACTCAGTAC
GCAAGGCTACCATTTGCTGATTGAGGGAACCTTGCGAACTACTCAAGTTCCTCGTCAGACTGCTCAATTATTATCTTCTA
AAGGTTACCAAGTTTCCTTAGCAGTGATTGGTACCAAACCAGAGCTTTCTTATCTCAGCACCTTGATTCGTTACGAAGAG
CTTTATGCCATCGATCCGACTCAGGCTAGAGCAACACCAAAAGAACACCACGATGGGATTGTTGAGAACTTGGTTGATAA
CTTGAGGGAGTTAGAAAGTGAAAATCTCTTTGACCAGATTCAAATTTATCAAAGAGATAGAACTTGTATCTATGATTCTG
AAACTGCTGAAGGTTCCGCAGCAGAAGTGCTACAAGAATGCCTATTTGGAAAATGTAGTAAGGTTGAGGAAGAGATGATG
AAGTTAGGTCGGGAACGGTTAGTTAAACTGAATAATAAGAATTTGCTGGAGAGTAACTATGGAATTTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT222704 WP_011409027.1 NZ_CP086195:c3458694-3458095 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT222704 NZ_CP118043:685548-686024 [Streptococcus agalactiae]
ATGATTGGAGACAATATTAAATCACTACGCCGAACACACGATTTAACACAACCAGAATTTGCGAAAATGGTCGGGATTTC
ACGCAATAGCCTGAGTCGCTACGAAAATGGAACCAGCACCGTTTCAACAGAACTCATTGACCGCATTTGTCAGAAATTTA
ACGTTTCTTATGTCGATATTGTAGGAGAGGACAAGATGCTAACACCTGTTGAAGATTACCAACTGACTTTAAAAATAGAA
GTGATAAAAGAACGTGGAGCAGCCATTTTATCTCAACTCTATCGATATCAGGATAGTCAAGATATTGCTTTTGATGATGA
AACAAATCCTTGGATTTTGATGAGTGATGATTTGGCTGAATTGATCAATACGAAAATATACCTTGTCGATACTTTCGATG
AAATAGAGCGTTACAATGGCTATTTAGACGGTATCGAGCGGATGTTAGACATGGTGCATCATCGGGTGGTGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References