222701

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 545018..545368 Replicon chromosome
Accession NZ_CP086195
Organism Xanthomonas oryzae strain JS158-2

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag LL925_RS02600 Protein ID WP_011257368.1
Coordinates 545234..545368 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag LL925_RS02595 Protein ID WP_011407410.1
Coordinates 545018..545170 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL925_RS02570 (LL925_02565) 541289..541972 - 684 WP_011257363.1 dTMP kinase -
LL925_RS02575 (LL925_02570) 542452..542994 - 543 Protein_494 GTPase -
LL925_RS02580 (LL925_02575) 542991..543455 - 465 Protein_495 hypothetical protein -
LL925_RS02585 (LL925_02580) 543447..543665 - 219 Protein_496 hypothetical protein -
LL925_RS02590 (LL925_02585) 543987..544910 + 924 WP_011407409.1 arginase -
LL925_RS02595 (LL925_02590) 545018..545170 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
LL925_RS02600 (LL925_02595) 545234..545368 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
LL925_RS02605 (LL925_02600) 545612..545821 + 210 WP_011407411.1 CsbD family protein -
LL925_RS02610 (LL925_02605) 545990..547279 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
LL925_RS02615 (LL925_02610) 547410..548354 + 945 WP_041181936.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T222701 WP_011257368.1 NZ_CP086195:545234-545368 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T222701 NZ_CP118043:c246871-246593 [Streptococcus agalactiae]
ATGTATCAAGTCAAGTTCACCTCTACTTTTAAAAAGAGCTATAAAAGGATTAAAAAGCGAGGCTTAGAGATGACACTCTT
AGATGAAGTGATTGAAAAACTCCGTCTAGGTCAGACACTCGAAGAAAAATACCGTGACCATGAACTCAAAGGAAACTTTG
TTGGCTTTAGGGAATGTCATATTAAACCAGATTGGCTCTTGATTTATCTGATTGAAGACGATATTTTGACTTTAACCTTA
GCCGACACAGGCAGTCATGCGGATTTGTTTAAGATGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT222701 WP_011407410.1 NZ_CP086195:545018-545170 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT222701 NZ_CP118043:c247144-246872 [Streptococcus agalactiae]
ATGGCAACTGTACCAACTCAAATTCGGATTGATGAAACTGTAAAAGCCCAAGCAACTTCATTATTTAATGACTTGGGAAT
GGATATGTCTAGTGCGGTCAATATTTTTCTTCGTCAATGTCTATTGCGTGGTGGACTTCCTTTCACAGTTGAAGTTCCTA
ATTATAGTCAAAAAACCTTAGAAGCTCTGGCAGAAGCTAAACGAATCTCTCGTGATAAAACGATCGCTTCTTATGACAAT
CTAGCAGATTTAAAGAAGGCTCTGGACGCTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References