222700

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4610998..4611348 Replicon chromosome
Accession NZ_CP086194
Organism Xanthomonas oryzae strain Z173

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag LL926_RS21660 Protein ID WP_011257368.1
Coordinates 4610998..4611132 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag LL926_RS21665 Protein ID WP_011407410.1
Coordinates 4611196..4611348 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL926_RS21645 (LL926_21600) 4608012..4608956 - 945 WP_041181936.1 MBL fold metallo-hydrolase -
LL926_RS21650 (LL926_21605) 4609087..4610376 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
LL926_RS21655 (LL926_21610) 4610545..4610754 - 210 WP_011407411.1 CsbD family protein -
LL926_RS21660 (LL926_21615) 4610998..4611132 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
LL926_RS21665 (LL926_21620) 4611196..4611348 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
LL926_RS21670 (LL926_21625) 4611456..4612379 - 924 WP_011407409.1 arginase -
LL926_RS21675 (LL926_21630) 4612701..4612919 + 219 Protein_4143 hypothetical protein -
LL926_RS21680 (LL926_21635) 4612911..4613375 + 465 Protein_4144 hypothetical protein -
LL926_RS21685 (LL926_21640) 4613372..4613914 + 543 Protein_4145 GTPase -
LL926_RS21690 (LL926_21645) 4614394..4615077 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T222700 WP_011257368.1 NZ_CP086194:c4611132-4610998 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T222700 NZ_CP118035:2785462-2785722 [Lacticaseibacillus rhamnosus]
ATGATTAAAACCTGGACCGATGATGCTTGGGCGGACTACATGTATTGGCATGATCAAAACGACAAGCGGACAATCAAACG
AATTAATCAACTCATTCAAGCCATTGACCGTGACCCTTATAAAGGCATCGGAAAACCTGAGCCACTTAGATATGCGCTAA
CCGGAAAATGGTCACGTCGGATTGATCAGGAAAATCGCATCATCTACAGCATTGAAAAGAACCACATTAATATTTTCGCC
TGCCGCACTCACTACAGTTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT222700 WP_011407410.1 NZ_CP086194:c4611348-4611196 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT222700 NZ_CP118035:2785200-2785469 [Lacticaseibacillus rhamnosus]
ATGGAAGCAACGAATTATAGTGATTTCCGCCGCAACCTTAAGCATTATATGAGTCAAGTCAACGAAGACGCCGAACCGCT
ACTGGTTACCGCTAAAGATGATGATGACAATGTGGTGGTTATGAGCAAGCACGATTTTGACGCCATCGAAGAAACCCTGT
ATTTACTCAGCAATCCCAAGCTGATGGCCAAAATCAAACGTGGTGATGCCCAAATTGCCGCTGGAAAGGCTAAACAGCAC
GAGTTGTTAACGGACTTCGATCATGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References