Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3956305..3957050 Replicon chromosome
Accession NZ_CP086194
Organism Xanthomonas oryzae strain Z173

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag LL926_RS18480 Protein ID WP_199285672.1
Coordinates 3956305..3956634 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag LL926_RS18485 Protein ID WP_011407754.1
Coordinates 3956631..3957050 (+) Length 140 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL926_RS18450 (LL926_18425) 3951436..3952107 + 672 WP_011407759.1 class I SAM-dependent methyltransferase -
LL926_RS18460 (LL926_18435) 3952409..3953200 - 792 WP_011407758.1 polysaccharide deacetylase family protein -
LL926_RS18465 (LL926_18440) 3953246..3954172 + 927 WP_011257932.1 Grx4 family monothiol glutaredoxin -
LL926_RS18470 (LL926_18445) 3954504..3954839 + 336 WP_011407757.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
LL926_RS18475 (LL926_18450) 3954883..3956202 - 1320 WP_011407756.1 IS701 family transposase -
LL926_RS18480 (LL926_18455) 3956305..3956634 + 330 WP_199285672.1 DUF4433 domain-containing protein Toxin
LL926_RS18485 (LL926_18460) 3956631..3957050 + 420 WP_011407754.1 macro domain-containing protein Antitoxin
LL926_RS18490 (LL926_18465) 3957102..3958069 + 968 WP_011258188.1 IS5-like element ISXo1 family transposase -
LL926_RS18495 (LL926_18470) 3958222..3958860 + 639 WP_011407753.1 phosphate phosphatase -
LL926_RS18500 (LL926_18475) 3958898..3960133 - 1236 WP_011257570.1 ISL3-like element ISXoo13 family transposase -
LL926_RS18505 (LL926_18480) 3960435..3960761 + 327 Protein_3547 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 3954883..3960133 5250


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(3-108)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 13145.86 Da        Isoelectric Point: 7.1160

>T222699 WP_199285672.1 NZ_CP086194:3956305-3956634 [Xanthomonas oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Download         Length: 330 bp

>T222699 NZ_CP118035:c2600144-2599761 [Lacticaseibacillus rhamnosus]
ATGGATGTAACAGTCAAACGCGGGGATGTATTTTTCGCCGATTTATCGCCGGTTGTCGGGTCGGAACAAGGCGGCAACCG
GCCCGTACTTATTATTCAAAACAATGTTGGTAACCATTATAGCCCCACTGTTATCGTGGCTGCCATTACCTCCAAAATCC
AAAAACCCAAAATGCCCACCCATGTCGGTTTGCGCGCCAAGCAAGACGGGGTTGAGCGTAATTCAGTCATTTTGCTTGAA
CAGATTCGTACAATTGATAAGCAACGGTTACAGGCACGCGTTACCGCTCTTTCAAGTGCCAAAATGGCAGCGGTGGATCG
GGCACTGGCGATATCGGTCGGACTCGTCAGCTTGCCTAAGCCGAAAACATATAATAAAAACTAA

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15607.02 Da        Isoelectric Point: 6.4733

>AT222699 WP_011407754.1 NZ_CP086194:3956631-3957050 [Xanthomonas oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Download         Length: 420 bp

>AT222699 NZ_CP118035:c2600412-2600164 [Lacticaseibacillus rhamnosus]
ATGAAGAAGGAAACGTCAGTAACGGTCGCGCTTGATAGTGCTATCAAAGCGCGTTTGGATGCCTATTGCGAGTTGAATGA
TATGGGTGTTCAGGATGTCATTACTGAAGCAGTGGCGAAGTTTTTGCAGTCACAAGCACCTGAGATCAATCAATTGATTT
CTGGCTATGTGGCAATGGGACAAATCAATACGGAAATCAGCCATGCTTTCTCCGCCTGCGAAAGTGAGGCATACGCCCAT
ATTCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References