Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1660039..1661558 Replicon chromosome
Accession NZ_CP086194
Organism Xanthomonas oryzae strain Z173

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag LL926_RS07905 Protein ID WP_011259680.1
Coordinates 1660635..1661558 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag LL926_RS07900 Protein ID WP_011409027.1
Coordinates 1660039..1660638 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL926_RS07865 (LL926_07855) 1655721..1656257 - 537 WP_011409032.1 lipocalin family protein -
LL926_RS07875 (LL926_07865) 1656527..1656994 - 468 WP_181718264.1 hypothetical protein -
LL926_RS07880 (LL926_07870) 1656975..1657265 - 291 WP_011409031.1 hypothetical protein -
LL926_RS07885 (LL926_07875) 1657764..1658795 + 1032 WP_042465093.1 IS630 family transposase -
LL926_RS07890 (LL926_07880) 1658777..1659352 - 576 WP_011409029.1 BrxE family protein -
LL926_RS07895 (LL926_07885) 1659384..1659656 - 273 WP_241847193.1 FaeA/PapI family transcriptional regulator -
LL926_RS07900 (LL926_07890) 1660039..1660638 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LL926_RS07905 (LL926_07895) 1660635..1661558 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LL926_RS07910 (LL926_07900) 1661638..1662108 - 471 WP_228383551.1 helix-turn-helix domain-containing protein -
LL926_RS07915 (LL926_07905) 1662574..1662816 + 243 WP_011409025.1 hypothetical protein -
LL926_RS07920 (LL926_07910) 1663268..1664233 - 966 Protein_1514 IS1595-like element ISXo5 family transposase -
LL926_RS07925 (LL926_07915) 1664328..1664816 + 489 WP_011409022.1 hypothetical protein -
LL926_RS07930 (LL926_07920) 1664833..1665365 - 533 Protein_1516 methyltransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T222697 WP_011259680.1 NZ_CP086194:1660635-1661558 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T222697 NZ_CP118035:c521678-521493 [Lacticaseibacillus rhamnosus]
TTGCAGCGTCAAGGTCATGTAAAATTAGCTTCTCTACATGACCATGCTTTAAAGGGTGCTCACAGCGGCGAACGAGCATT
GCGTGTTGCTCCTGATTGGCTTCTCGTTTATAAAGTCGATGCTGAAGCGTTAATTTTAATGCTTCTTGCAACAGGCACAC
ACCGCGATACATTGAACATTGAGTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT222697 WP_011409027.1 NZ_CP086194:1660039-1660638 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT222697 NZ_CP118035:c521978-521706 [Lacticaseibacillus rhamnosus]
ATGACCAAAAAATCCCGCATCAGCGTTAGGATTGATACCAAAACTAAAGAACGAGCGCTCCATGTTCTTAATAGCATGGG
ATTAGATATTTCCTCGGCTATTAACATGTACCTGAAACGGATTGGTGACACCGGTGCATTGCCATTTACACCTCCAATGT
CATTTGTTGATCAGCTTCAAGTTGCAGAAGCTGATGTTAAAGCGGGGCGAATAAAAAGCTTCAAGACTGTCGATGCTTTG
ATGAAGGATTTATACAGTGATGTTGACGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References