Detailed information of TA system TA222695

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 3812072..3812817
• Replicon: chromosome
• Accession: NZ_CP086193
• Organism: Xanthomonas oryzae strain GDV

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: LL918_RS17985
• Protein ID: WP_199285672.1
• Coordinates: 3812488..3812817 (-)
• Length: 110 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: -
• Locus tag: LL918_RS17980
• Protein ID: WP_011407754.1
• Coordinates: 3812072..3812491 (-)
• Length: 140 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LL918_RS17960 (LL918_17940)	3808360..3808686	-	327	Protein_3429	hypothetical protein	-
LL918_RS17965 (LL918_17945)	3808988..3810223	+	1236	WP_011257570.1	ISL3-like element ISXoo13 family transposase	-
LL918_RS17970 (LL918_17950)	3810261..3810917	-	657	WP_075246166.1	phosphate phosphatase	-
LL918_RS17975 (LL918_17955)	3811052..3812020	-	969	WP_011258802.1	IS5-like element ISXo1 family transposase	-
LL918_RS17980 (LL918_17960)	3812072..3812491	-	420	WP_011407754.1	macro domain-containing protein	Antitoxin
LL918_RS17985 (LL918_17965)	3812488..3812817	-	330	WP_199285672.1	DUF4433 domain-containing protein	Toxin
LL918_RS17990 (LL918_17970)	3812920..3814239	+	1320	WP_155296575.1	IS701-like element ISXo15 family transposase	-
LL918_RS17995 (LL918_17975)	3814283..3814618	-	336	WP_011407757.1	DarT ssDNA thymidine ADP-ribosyltransferase family protein	-
LL918_RS18000 (LL918_17980)	3814950..3815876	-	927	WP_011257932.1	Grx4 family monothiol glutaredoxin	-
LL918_RS18005 (LL918_17985)	3815922..3816713	+	792	WP_011407758.1	polysaccharide deacetylase family protein	-
LL918_RS18015 (LL918_17995)	3817015..3817686	-	672	WP_011407759.1	class I SAM-dependent methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	3808988..3814239	5251

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (3-108)

Antitoxin

• Macro domain (18-130)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 13145.86 Da
• Isoelectric Point: 7.1160

>T222695 WP_199285672.1 NZ_CP086193:c3812817-3812488 [Xanthomonas oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Nucleotide

• Length: 330 bp

>T222695 NZ_CP118032:c693866-693603 [Lactobacillus gasseri]
ATGAATGTAATTTGGTCAGATGAATCTTGGGACGACTTTGAATATTGGCTAGACAATGATAAGCGAAATGTCAAAAAGAT
ACGTAAATTAATAAAAGATACTAAAAGACATCCCTTTGATGGAATTGGTAAGCCTGAGCCACTTCACGATAATTTATCAG
GATTGTGGTCTAGAAGAATTACAGACGAGCATCGTTTCGTTTACTATGTGGAGAACAATAGTTTGTACATCGTATCAGCA
AGATTTCATTATTCTAATGATTAG

Antitoxin

Protein

• Length: 140 a.a.
• Molecular weight: 15607.02 Da
• Isoelectric Point: 6.4733

>AT222695 WP_011407754.1 NZ_CP086193:c3812491-3812072 [Xanthomonas oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Nucleotide

• Length: 420 bp

>AT222695 NZ_CP118032:c694117-693866 [Lactobacillus gasseri]
ATGCAAGCAGAGGCTTATTCAAACGTTAGAAATAACCTTAAATCATTTATGAAACAAGTAAATGATAATTCTGAAGCAAT
AATTATTACTTCTAGAAATAGTGAAGATAATTCTGTTCTCATCAGCAAAGCAGATTATGATAACCTTGTCGAAAATGCTT
ATATTAGAAGCTCCACTGCCAACATGGATCACATTTTAAAATCATTGAAGCAATTAAAAAACGGCAAAGGCAAGGAGCAT
AACTGGGAATAA