Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | EcnAB/- |
| Location | 3153289..3153639 | Replicon | chromosome |
| Accession | NZ_CP086193 | ||
| Organism | Xanthomonas oryzae strain GDV | ||
Toxin (Protein)
| Gene name | EcnB | Uniprot ID | G7TLC7 |
| Locus tag | LL918_RS14770 | Protein ID | WP_011257368.1 |
| Coordinates | 3153505..3153639 (+) | Length | 45 a.a. |
Antitoxin (Protein)
| Gene name | EcnA | Uniprot ID | G7TLC8 |
| Locus tag | LL918_RS14765 | Protein ID | WP_011407410.1 |
| Coordinates | 3153289..3153441 (+) | Length | 51 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LL918_RS14740 (LL918_14720) | 3149560..3150243 | - | 684 | WP_011257363.1 | dTMP kinase | - |
| LL918_RS14745 (LL918_14725) | 3150723..3151265 | - | 543 | Protein_2824 | GTPase | - |
| LL918_RS14750 (LL918_14730) | 3151262..3151726 | - | 465 | Protein_2825 | hypothetical protein | - |
| LL918_RS14755 (LL918_14735) | 3151718..3151936 | - | 219 | Protein_2826 | hypothetical protein | - |
| LL918_RS14760 (LL918_14740) | 3152258..3153181 | + | 924 | WP_011407409.1 | arginase | - |
| LL918_RS14765 (LL918_14745) | 3153289..3153441 | + | 153 | WP_011407410.1 | entericidin A/B family lipoprotein | Antitoxin |
| LL918_RS14770 (LL918_14750) | 3153505..3153639 | + | 135 | WP_011257368.1 | entericidin A/B family lipoprotein | Toxin |
| LL918_RS14775 (LL918_14755) | 3153883..3154092 | + | 210 | WP_011407411.1 | CsbD family protein | - |
| LL918_RS14780 (LL918_14760) | 3154261..3155550 | + | 1290 | WP_069959696.1 | tryptophan--tRNA ligase | - |
| LL918_RS14785 (LL918_14765) | 3155681..3156625 | + | 945 | WP_027704118.1 | MBL fold metallo-hydrolase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 45 a.a. Molecular weight: 4457.33 Da Isoelectric Point: 10.2040
>T222694 WP_011257368.1 NZ_CP086193:3153505-3153639 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK
Download Length: 135 bp
>T222694 NZ_CP118029:1385240-1386076 [Streptococcus anginosus]
GTGAACAAAGCAAAATTAACGGCACTCTGCCATAAAGTTTCAAAAGAAACAGGATTAACGTTTAATTCTGTGATGACCTA
CTACTTCCTGGAAATTATTCTGAAAAAATTGAGCCAAAGCGCTTATGCTCAAAATTACATTTTCAAAGGAGGTTTTCTGC
TCTCAAACGTCGTCGGGGTTGCTTCCCGTAGTACCGTTGACATTGACTTTCTCTTTAGTAAAATGAATCTATCAGAAGAG
ACCGTGCATCAGCAATTGGAGGATATCCTTGGAAAATCTGATGAAGATATTTCTTTCACTATTCAGTCGGTCACAGCAAT
TAAGGAAAGTGATGATTACGGAGGTTATCGTGCAAGTATCCTTTGCCAGCTTGAGAACATCAGACAGGTCATCCACCTAG
ATATTGCGACTGGGGACATTGTCACTCCGCAGCCCATCACTTACGACTACAAGCCAATCTTCACATCAGAACAGTTTCCT
ATCATTGCCTACACGATTGAGACTATCTTAGCAGAGAAACTACAAACTATTTATTCTCGCAGCTTCTTGAATAGTCGAAG
CAAAGACTTCTATGACGTCTATATCTTGTCAAAATTGAAGAAATCAGAAATTGATTCGCAGCAACTTCTCACTGCTTGTC
AGCGTACCTTCGATTATCGAGGTACTGAATTAGACTTCGATAAATTCATCAATCTGCTAGAAACATTCAAAACTGATTCA
ACCCAAAACCATCAGTGGGAAAACTACTCTAAAAAGTATAGTTACACTAAAGGTATTACATTTAACGATGTTCTGACAGA
GATGACTGATTTGCTTGTAACTATCAAAAATCTCTAA
GTGAACAAAGCAAAATTAACGGCACTCTGCCATAAAGTTTCAAAAGAAACAGGATTAACGTTTAATTCTGTGATGACCTA
CTACTTCCTGGAAATTATTCTGAAAAAATTGAGCCAAAGCGCTTATGCTCAAAATTACATTTTCAAAGGAGGTTTTCTGC
TCTCAAACGTCGTCGGGGTTGCTTCCCGTAGTACCGTTGACATTGACTTTCTCTTTAGTAAAATGAATCTATCAGAAGAG
ACCGTGCATCAGCAATTGGAGGATATCCTTGGAAAATCTGATGAAGATATTTCTTTCACTATTCAGTCGGTCACAGCAAT
TAAGGAAAGTGATGATTACGGAGGTTATCGTGCAAGTATCCTTTGCCAGCTTGAGAACATCAGACAGGTCATCCACCTAG
ATATTGCGACTGGGGACATTGTCACTCCGCAGCCCATCACTTACGACTACAAGCCAATCTTCACATCAGAACAGTTTCCT
ATCATTGCCTACACGATTGAGACTATCTTAGCAGAGAAACTACAAACTATTTATTCTCGCAGCTTCTTGAATAGTCGAAG
CAAAGACTTCTATGACGTCTATATCTTGTCAAAATTGAAGAAATCAGAAATTGATTCGCAGCAACTTCTCACTGCTTGTC
AGCGTACCTTCGATTATCGAGGTACTGAATTAGACTTCGATAAATTCATCAATCTGCTAGAAACATTCAAAACTGATTCA
ACCCAAAACCATCAGTGGGAAAACTACTCTAAAAAGTATAGTTACACTAAAGGTATTACATTTAACGATGTTCTGACAGA
GATGACTGATTTGCTTGTAACTATCAAAAATCTCTAA
Antitoxin
Download Length: 51 a.a. Molecular weight: 5046.99 Da Isoelectric Point: 8.7942
>AT222694 WP_011407410.1 NZ_CP086193:3153289-3153441 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC
Download Length: 153 bp
>AT222694 NZ_CP118029:1384653-1385243 [Streptococcus anginosus]
ATGTCTAATAAAGAAACCGTTCTGAATTATCTCAAACAGAATAACGGTATCATTACATATAAAGACTGTAAAGAGCTTGG
GGTTCCAGCTGTCTATCTCTCACGACTTGAAAATGAAGAGAAAATATTCCGAGTGGACAAGGGCATCTATCTTTCTACCG
ATGGTGACTATGACGAGTACTACTTCTTCCAATACAGATTTTCAAGAGCTATTTACTCCTATGTTTCCGCTCTTTATCTT
CAAGGGTTCACGGATGAAATCCCTCAATATTTTGAAGTCACCGTACCAAGAGGGTATCGTTTCAATAATCCGCCTCAAAA
CCTTGCGGTTCATACCGTCCCAAAGGAAATTGTTGACCTTGGTGTTATCTCTGTAAAGACACCCTGGGGACAGACCGTTA
AGACCTACGACTTTGAGCGTATCATCTGTGACTTTATTCAAAATCGTAAAAAAATTGATAATGAACTTTTCGCCAAAACT
CTTAAGGCTTATGTCAACTATCCAAATAAAAACCTGACAAACCTTTACCAATACGCTGAAAAAATGAAAATTATCAATCA
AACAAAACAAACACTTGAGGTGCTAATGTGA
ATGTCTAATAAAGAAACCGTTCTGAATTATCTCAAACAGAATAACGGTATCATTACATATAAAGACTGTAAAGAGCTTGG
GGTTCCAGCTGTCTATCTCTCACGACTTGAAAATGAAGAGAAAATATTCCGAGTGGACAAGGGCATCTATCTTTCTACCG
ATGGTGACTATGACGAGTACTACTTCTTCCAATACAGATTTTCAAGAGCTATTTACTCCTATGTTTCCGCTCTTTATCTT
CAAGGGTTCACGGATGAAATCCCTCAATATTTTGAAGTCACCGTACCAAGAGGGTATCGTTTCAATAATCCGCCTCAAAA
CCTTGCGGTTCATACCGTCCCAAAGGAAATTGTTGACCTTGGTGTTATCTCTGTAAAGACACCCTGGGGACAGACCGTTA
AGACCTACGACTTTGAGCGTATCATCTGTGACTTTATTCAAAATCGTAAAAAAATTGATAATGAACTTTTCGCCAAAACT
CTTAAGGCTTATGTCAACTATCCAAATAAAAACCTGACAAACCTTTACCAATACGCTGAAAAAATGAAAATTATCAATCA
AACAAAACAAACACTTGAGGTGCTAATGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0C5UG40 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0C5V759 |