Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1137200..1138719 Replicon chromosome
Accession NZ_CP086193
Organism Xanthomonas oryzae strain GDV

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag LL918_RS05100 Protein ID WP_011259680.1
Coordinates 1137200..1138123 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag LL918_RS05105 Protein ID WP_011409027.1
Coordinates 1138120..1138719 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL918_RS05075 (LL918_05070) 1133393..1133925 + 533 Protein_973 methyltransferase domain-containing protein -
LL918_RS05080 (LL918_05075) 1133942..1134430 - 489 WP_069959937.1 hypothetical protein -
LL918_RS05085 (LL918_05080) 1134525..1135490 + 966 Protein_975 IS1595-like element ISXo5 family transposase -
LL918_RS05090 (LL918_05085) 1135942..1136184 - 243 WP_011409025.1 hypothetical protein -
LL918_RS05095 (LL918_05090) 1136650..1137120 + 471 WP_228329666.1 helix-turn-helix domain-containing protein -
LL918_RS05100 (LL918_05095) 1137200..1138123 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LL918_RS05105 (LL918_05100) 1138120..1138719 - 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LL918_RS05110 (LL918_05105) 1139084..1139374 + 291 WP_228329665.1 FaeA/PapI family transcriptional regulator -
LL918_RS05115 (LL918_05110) 1139406..1139981 + 576 WP_011409029.1 BrxE family protein -
LL918_RS05120 (LL918_05115) 1139963..1140994 - 1032 WP_042465093.1 IS630 family transposase -
LL918_RS05125 (LL918_05120) 1141493..1141783 + 291 WP_011409031.1 hypothetical protein -
LL918_RS05130 (LL918_05125) 1141764..1142231 + 468 WP_181718264.1 hypothetical protein -
LL918_RS05140 (LL918_05135) 1142501..1143037 + 537 WP_011409032.1 lipocalin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T222692 WP_011259680.1 NZ_CP086193:c1138123-1137200 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T222692 NZ_CP118021:675443-676189 [Bacillus spizizenii]
ATGCTTTTATTCTTTCAGATCATGGTCTGGTGCATCATGGCCGGATTGGGCTTATACGTGTATGCCACGTGGCGTTTCGA
AGCGAAGGTCAAAGAAAAAATGTCCGCTATCCGGAAAACATGGTATTTGCTGTTTGTTCTGGGCGCTATGGTATACTGGA
CATATGATTCCTCTTCCCTGTTTACTCACTGGGAACGGTATCTCATTGTCGCCGTCAGTTTTGCTTTAATTGACGCTTTC
ATCTTCTTAAGCGCATACGTCAAAAAACTGGCCGGCAGCGAACTGGAAACAGACACAAGAGAAATTCTCGAAGAAAACAA
CGAAATGCTCCACATGTATCTCAATCGGCTGAAAACATACCAATACCTATTGAAAAACGAACCGATCCACGTTTATTATG
GAAGTATAGAAGCATATGCTGAAGGTATTGATAAACTGCTGAAAACCTATGCCGATAAAATGAACTTAACGGCCTCCCTT
TGTCACTATTCGACACAGGCTGATAAAAACCGGTTAACAGAGCATATGGACGATCCGGCAGACGTGCAAACTCGTCTTGA
TCGAAAGGATGTTTATTACGACCAATACGGAAAAGTGGTTCTCATCCCTTTTATCATCGAGACACAGAGTTACGTCATCA
AGCTGACGTCTGACAGCATTGTCACGGAATTTGATTATTTGCTTTTCACATCATTAACGAGCATATATGATTTGGTGCTG
CCAATTGAGGAGGAAGGTGAAGGATAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT222692 WP_011409027.1 NZ_CP086193:c1138719-1138120 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT222692 NZ_CP118021:676189-676359 [Bacillus spizizenii]
ATGGAACGCGCATTTCAAAACGGATGCGAGCCCCGCGCGGCGAAGTCGTTTAAAATCCTGAAGAAACGTTCAACCACCAG
TGTCGCAAGCTATCAAGTCAGCCCGCATACAGCAAGAATCTTCAAAGAAAACGAACGGCTGATTGACGAGTATAAACGAA
AAAAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References