Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | EcnAB/- |
| Location | 2094235..2094585 | Replicon | chromosome |
| Accession | NZ_CP086191 | ||
| Organism | Xanthomonas oryzae strain JS49-6 | ||
Toxin (Protein)
| Gene name | EcnB | Uniprot ID | G7TLC7 |
| Locus tag | LL928_RS09885 | Protein ID | WP_011257368.1 |
| Coordinates | 2094451..2094585 (+) | Length | 45 a.a. |
Antitoxin (Protein)
| Gene name | EcnA | Uniprot ID | G7TLC8 |
| Locus tag | LL928_RS09880 | Protein ID | WP_011407410.1 |
| Coordinates | 2094235..2094387 (+) | Length | 51 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LL928_RS09855 (LL928_09845) | 2090515..2091198 | - | 684 | WP_011257363.1 | dTMP kinase | - |
| LL928_RS09860 (LL928_09850) | 2091678..2092220 | - | 543 | Protein_1886 | GTPase | - |
| LL928_RS09865 (LL928_09855) | 2092217..2092672 | - | 456 | Protein_1887 | hypothetical protein | - |
| LL928_RS09870 (LL928_09860) | 2092664..2092882 | - | 219 | Protein_1888 | hypothetical protein | - |
| LL928_RS09875 (LL928_09865) | 2093204..2094127 | + | 924 | WP_011407409.1 | arginase | - |
| LL928_RS09880 (LL928_09870) | 2094235..2094387 | + | 153 | WP_011407410.1 | entericidin A/B family lipoprotein | Antitoxin |
| LL928_RS09885 (LL928_09875) | 2094451..2094585 | + | 135 | WP_011257368.1 | entericidin A/B family lipoprotein | Toxin |
| LL928_RS09890 (LL928_09880) | 2094826..2095035 | + | 210 | WP_011407411.1 | CsbD family protein | - |
| LL928_RS09895 (LL928_09885) | 2095204..2096493 | + | 1290 | WP_069959696.1 | tryptophan--tRNA ligase | - |
| LL928_RS09900 (LL928_09890) | 2096624..2097568 | + | 945 | WP_027704118.1 | MBL fold metallo-hydrolase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 45 a.a. Molecular weight: 4457.33 Da Isoelectric Point: 10.2040
>T222688 WP_011257368.1 NZ_CP086191:2094451-2094585 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK
Download Length: 135 bp
>T222688 NZ_CP118014:c4929096-4928149 [Escherichia coli]
ATGGATGATTTAACCACTCTTTTTTCTGAAGTGGCTGACGCGCTTGGTATTGAGTCTGTCGCAATTGTGGAAAAAGATCA
CTATATCGTTGAGCTTTTGCAATTGCTTAAACCTCTGGTGTTCGATACTCATCAATTGGTGTTTGCCGGAGGAACCGCTC
TGGCAAAATCAGGTGTCGCACTTAATCGCATGTCGGAAGATGTGGATATCAAACTGGTGCCTAAGGATGCATTTCAGGCA
CTTTCCCGCACTCAGCGAAAAAATACCCGTAAAGAAATTGTTCAGGCAGTTTCCAGTGCAATAGCTTCATCGGGTGTGTT
CAATTTTGATGATGATTACCCAAAAGTGACGCGGGATGAATATCGTTATAATGACATACCTGTTCGTTATCCACAGCGAG
TGGTGCAGGCACCTTGTTTGCGTCCTTTTATCCGGCTGGAACTGATGGAAGCGAAGTTACTGGAGCCTTCTGAATTACGG
GATATTCATTCACTGGTAACAGGGAGCACGGGAAAAGCGGCTATTGTTTCAGCGTTTCCATGCGCAACTATCATTAGCAC
ACAGGCTGAAAAGCTGGTGGCGATGTTACGTCGTACTGCGGCAGTTGTGCGAGATGTTGAGCGATTTGATGATGCATCGC
TGGTACGTCATATCTACGATACAAACTGTATTGTTGAGACGAGTCATGTTGATATGAGTCTGCTCGTTGATTTTGTTCAA
CAAACTATTGAGCAGGACATTCAGCGTTACGGCAACCAGTACCCGCAGTTTTGTGCGTCTCCAGTTGATGAGCTAAAAAT
GGGACTGGATGAGTTGGCGAACAATCCTCTCTACCAGATGCGCTATCAGCAGTTTGTTTCGCCAATGGTGTATGGAGAGC
GAAAGATCACATGGGATGAGGCTTACTCCAGGTTTAGGAGCTTAGCGCTAGCCATCCTGAATGCTTGA
ATGGATGATTTAACCACTCTTTTTTCTGAAGTGGCTGACGCGCTTGGTATTGAGTCTGTCGCAATTGTGGAAAAAGATCA
CTATATCGTTGAGCTTTTGCAATTGCTTAAACCTCTGGTGTTCGATACTCATCAATTGGTGTTTGCCGGAGGAACCGCTC
TGGCAAAATCAGGTGTCGCACTTAATCGCATGTCGGAAGATGTGGATATCAAACTGGTGCCTAAGGATGCATTTCAGGCA
CTTTCCCGCACTCAGCGAAAAAATACCCGTAAAGAAATTGTTCAGGCAGTTTCCAGTGCAATAGCTTCATCGGGTGTGTT
CAATTTTGATGATGATTACCCAAAAGTGACGCGGGATGAATATCGTTATAATGACATACCTGTTCGTTATCCACAGCGAG
TGGTGCAGGCACCTTGTTTGCGTCCTTTTATCCGGCTGGAACTGATGGAAGCGAAGTTACTGGAGCCTTCTGAATTACGG
GATATTCATTCACTGGTAACAGGGAGCACGGGAAAAGCGGCTATTGTTTCAGCGTTTCCATGCGCAACTATCATTAGCAC
ACAGGCTGAAAAGCTGGTGGCGATGTTACGTCGTACTGCGGCAGTTGTGCGAGATGTTGAGCGATTTGATGATGCATCGC
TGGTACGTCATATCTACGATACAAACTGTATTGTTGAGACGAGTCATGTTGATATGAGTCTGCTCGTTGATTTTGTTCAA
CAAACTATTGAGCAGGACATTCAGCGTTACGGCAACCAGTACCCGCAGTTTTGTGCGTCTCCAGTTGATGAGCTAAAAAT
GGGACTGGATGAGTTGGCGAACAATCCTCTCTACCAGATGCGCTATCAGCAGTTTGTTTCGCCAATGGTGTATGGAGAGC
GAAAGATCACATGGGATGAGGCTTACTCCAGGTTTAGGAGCTTAGCGCTAGCCATCCTGAATGCTTGA
Antitoxin
Download Length: 51 a.a. Molecular weight: 5046.99 Da Isoelectric Point: 8.7942
>AT222688 WP_011407410.1 NZ_CP086191:2094235-2094387 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC
Download Length: 153 bp
>AT222688 NZ_CP118014:c4929484-4929089 [Escherichia coli]
ATGACGATAAAAGCACGCATTCAGTCACGACTGAAACGTTCTAAACGTTACGTATTCACTCGTGACGACTTTAAAGATAT
TGCAGGCTACGATCAGGTTGGTCGGGTATTGCGCGAGCTTGTCAGGGAAGGGCAACTGTTGAAGGTTGGTTATGGCGTGT
ATACCAAAGCACGGCGGAACGGTATTACAGGCAAGGTAATGCCAGCGGCTCCCGGAGGCTCTTCAGCGGTGATTGTCGAA
ACGCTGGAACGCCTGAAAGTACGCTATCGTTTTGCTGGCGCAACGCAGGCATACAATAGCGGTACTTCTACGCAGATCCC
AGCTTCACCCGAGATAAAAACCCCCCGGCGTTTTAAACGCGTATTATCTGTAGGGAACAGCAGATTAAATGGATGA
ATGACGATAAAAGCACGCATTCAGTCACGACTGAAACGTTCTAAACGTTACGTATTCACTCGTGACGACTTTAAAGATAT
TGCAGGCTACGATCAGGTTGGTCGGGTATTGCGCGAGCTTGTCAGGGAAGGGCAACTGTTGAAGGTTGGTTATGGCGTGT
ATACCAAAGCACGGCGGAACGGTATTACAGGCAAGGTAATGCCAGCGGCTCCCGGAGGCTCTTCAGCGGTGATTGTCGAA
ACGCTGGAACGCCTGAAAGTACGCTATCGTTTTGCTGGCGCAACGCAGGCATACAATAGCGGTACTTCTACGCAGATCCC
AGCTTCACCCGAGATAAAAACCCCCCGGCGTTTTAAACGCGTATTATCTGTAGGGAACAGCAGATTAAATGGATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0C5UG40 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0C5V759 |