Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 4190280..4190836 Replicon chromosome
Accession NZ_CP086188
Organism Xanthomonas oryzae strain PXO79

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LL930_RS19795 Protein ID WP_229001948.1
Coordinates 4190280..4190531 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A854CIX2
Locus tag LL930_RS19800 Protein ID WP_011408759.1
Coordinates 4190558..4190836 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL930_RS19750 (LL930_19720) 4186050..4187141 + 1092 WP_011408756.1 ribonuclease D -
LL930_RS19755 (LL930_19725) 4187238..4187554 - 317 Protein_3783 ATP-dependent DNA ligase -
LL930_RS19760 (LL930_19730) 4187836..4188012 - 177 Protein_3784 DUF3606 domain-containing protein -
LL930_RS19765 (LL930_19735) 4188234..4188635 + 402 WP_011259345.1 H-NS family nucleoid-associated regulatory protein -
LL930_RS19775 4189066..4189194 - 129 WP_012444694.1 hypothetical protein -
LL930_RS19780 (LL930_19745) 4189163..4189282 - 120 Protein_3787 IS3 family transposase -
LL930_RS19785 (LL930_19750) 4189499..4189753 - 255 WP_223293127.1 hypothetical protein -
LL930_RS19790 (LL930_19755) 4189822..4190019 - 198 WP_153296741.1 hypothetical protein -
LL930_RS19795 (LL930_19760) 4190280..4190531 - 252 WP_229001948.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LL930_RS19800 (LL930_19765) 4190558..4190836 - 279 WP_011408759.1 CopG family ribbon-helix-helix protein Antitoxin
LL930_RS19805 (LL930_19770) 4191032..4191376 - 345 WP_198912817.1 hypothetical protein -
LL930_RS19810 (LL930_19775) 4191770..4192725 - 956 Protein_3793 IS30-like element IS1112b family transposase -
LL930_RS19820 (LL930_19785) 4194498..4195682 - 1185 WP_011408397.1 IS256-like element IS1113 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-81)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9603.92 Da        Isoelectric Point: 9.9718

>T222683 WP_229001948.1 NZ_CP086188:c4190531-4190280 [Xanthomonas oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Download         Length: 252 bp

>T222683 NZ_CP118014:3395072-3395179 [Escherichia coli]
ATGACGCTCGCGAAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10826.11 Da        Isoelectric Point: 4.9736

>AT222683 WP_011408759.1 NZ_CP086188:c4190836-4190558 [Xanthomonas oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT222683 NZ_CP118014:c3395019-3394958 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A854CIX2

References