Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 1602362..1602712 Replicon chromosome
Accession NZ_CP086188
Organism Xanthomonas oryzae strain PXO79

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag LL930_RS07630 Protein ID WP_011257368.1
Coordinates 1602578..1602712 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag LL930_RS07625 Protein ID WP_011407410.1
Coordinates 1602362..1602514 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL930_RS07600 (LL930_07590) 1598633..1599316 - 684 WP_011257363.1 dTMP kinase -
LL930_RS07605 (LL930_07595) 1599796..1600338 - 543 Protein_1464 GTPase -
LL930_RS07610 (LL930_07600) 1600335..1600799 - 465 Protein_1465 hypothetical protein -
LL930_RS07615 (LL930_07605) 1600791..1601009 - 219 Protein_1466 hypothetical protein -
LL930_RS07620 (LL930_07610) 1601331..1602254 + 924 WP_011407409.1 arginase -
LL930_RS07625 (LL930_07615) 1602362..1602514 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
LL930_RS07630 (LL930_07620) 1602578..1602712 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
LL930_RS07635 (LL930_07625) 1602956..1603165 + 210 WP_011407411.1 CsbD family protein -
LL930_RS07640 (LL930_07630) 1603334..1604623 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
LL930_RS07645 (LL930_07635) 1604754..1605698 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T222682 WP_011257368.1 NZ_CP086188:1602578-1602712 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T222682 NZ_CP118014:3394536-3394643 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT222682 WP_011407410.1 NZ_CP086188:1602362-1602514 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT222682 NZ_CP118014:c3394489-3394423 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References