Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2568039..2568389 Replicon chromosome
Accession NZ_CP086185
Organism Xanthomonas oryzae strain PXO112

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag LL920_RS11940 Protein ID WP_011257368.1
Coordinates 2568255..2568389 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag LL920_RS11935 Protein ID WP_011407410.1
Coordinates 2568039..2568191 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL920_RS11910 (LL920_11885) 2564310..2564993 - 684 WP_011257363.1 dTMP kinase -
LL920_RS11915 (LL920_11890) 2565473..2566015 - 543 Protein_2285 GTPase -
LL920_RS11920 (LL920_11895) 2566012..2566476 - 465 Protein_2286 hypothetical protein -
LL920_RS11925 (LL920_11900) 2566468..2566686 - 219 Protein_2287 hypothetical protein -
LL920_RS11930 (LL920_11905) 2567008..2567931 + 924 WP_011407409.1 arginase -
LL920_RS11935 (LL920_11910) 2568039..2568191 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
LL920_RS11940 (LL920_11915) 2568255..2568389 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
LL920_RS11945 (LL920_11920) 2568633..2568842 + 210 WP_011407411.1 CsbD family protein -
LL920_RS11950 (LL920_11925) 2569011..2570300 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
LL920_RS11955 (LL920_11930) 2570431..2571375 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T222680 WP_011257368.1 NZ_CP086185:2568255-2568389 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T222680 NZ_CP086185:2568255-2568389 [Xanthomonas oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT222680 WP_011407410.1 NZ_CP086185:2568039-2568191 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT222680 NZ_CP086185:2568039-2568191 [Xanthomonas oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References