Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 657152..658671 Replicon chromosome
Accession NZ_CP086185
Organism Xanthomonas oryzae strain PXO112

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag LL920_RS02950 Protein ID WP_011259680.1
Coordinates 657152..658075 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag LL920_RS02955 Protein ID WP_011409027.1
Coordinates 658072..658671 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL920_RS02920 (LL920_02905) 652751..652903 + 153 Protein_564 SAM-dependent methyltransferase -
LL920_RS02925 (LL920_02910) 653015..654391 + 1377 Protein_565 IS5 family transposase -
LL920_RS02930 (LL920_02915) 654411..654943 + 533 Protein_566 methyltransferase domain-containing protein -
LL920_RS02935 (LL920_02920) 654960..655469 - 510 WP_011259678.1 hypothetical protein -
LL920_RS02940 (LL920_02925) 655894..656136 - 243 WP_011259679.1 hypothetical protein -
LL920_RS02945 (LL920_02930) 656602..657072 + 471 WP_228329666.1 helix-turn-helix domain-containing protein -
LL920_RS02950 (LL920_02935) 657152..658075 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LL920_RS02955 (LL920_02940) 658072..658671 - 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LL920_RS02960 (LL920_02945) 659054..659326 + 273 WP_230455482.1 FaeA/PapI family transcriptional regulator -
LL920_RS02965 (LL920_02950) 659358..659846 + 489 WP_044756654.1 BrxE family protein -
LL920_RS02970 (LL920_02955) 659833..660630 - 798 WP_274392128.1 IS5 family transposase -
LL920_RS02975 (LL920_02960) 660766..661799 - 1034 Protein_575 IS630 family transposase -
LL920_RS02980 (LL920_02965) 662298..662588 + 291 WP_011409031.1 hypothetical protein -
LL920_RS02985 (LL920_02970) 662569..662943 + 375 WP_229002607.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 659833..660630 797


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T222678 WP_011259680.1 NZ_CP086185:c658075-657152 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T222678 NZ_CP118014:2669135-2669238 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT222678 WP_011409027.1 NZ_CP086185:c658671-658072 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT222678 NZ_CP118014:c2669276-2669005 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References