222675

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4164996..4165346 Replicon chromosome
Accession NZ_CP086184
Organism Xanthomonas oryzae strain PXO280

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag LL919_RS19475 Protein ID WP_011257368.1
Coordinates 4164996..4165130 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag LL919_RS19480 Protein ID WP_011407410.1
Coordinates 4165194..4165346 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL919_RS19460 (LL919_19415) 4162010..4162954 - 945 WP_027704118.1 MBL fold metallo-hydrolase -
LL919_RS19465 (LL919_19420) 4163085..4164374 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
LL919_RS19470 (LL919_19425) 4164543..4164752 - 210 WP_011407411.1 CsbD family protein -
LL919_RS19475 (LL919_19430) 4164996..4165130 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
LL919_RS19480 (LL919_19435) 4165194..4165346 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
LL919_RS19485 (LL919_19440) 4165454..4166377 - 924 WP_011407409.1 arginase -
LL919_RS19490 (LL919_19445) 4166699..4166917 + 219 Protein_3725 hypothetical protein -
LL919_RS19495 (LL919_19450) 4166909..4167373 + 465 Protein_3726 hypothetical protein -
LL919_RS19500 (LL919_19455) 4167370..4167912 + 543 Protein_3727 GTPase -
LL919_RS19505 (LL919_19460) 4168392..4169075 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T222675 WP_011257368.1 NZ_CP086184:c4165130-4164996 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T222675 NZ_CP118014:1954194-1954592 [Escherichia coli]
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCAGTACATGTCAGAGAGCGGTTTAA
CCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTGATGGAGCTTATCTATGGGGCAGAAAAAAGTCAGATGCCAG
AACGCAATTTGGCGGTGATTGAAGGTTTCGTATCTCGTTTGGAAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACC
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCTGTTGGACCTTTTGACCAGATGATAGCGGGACATGCTCGCAG
TCGCGGTTTGATTGTGGTTACCAACAATACCCGAGAGTTTGAGCGAGTGGCGGGAATCAGACTAGAAGATTGGAGCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT222675 WP_011407410.1 NZ_CP086184:c4165346-4165194 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT222675 NZ_CP118014:1953967-1954194 [Escherichia coli]
ATGGAAACTACTGTATTTTTAAGTAATCGCAGTCAGGCCGTCAGATTACCGAAAGCGGTCGCTCTGCCAGAGGATGTTAA
GAAAGTAGAAATTATTGCGATTGGTCGTACAAGAATCATCACTCCCGCCGGTGAGTCCTGGGACAGTTGGTTTGATGGCG
AAAATGTGAGTGCGGATTTTATGGATATCCGTGATCAACCCGCAATGCAGGAAAGGGAATCATTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References