Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1095659..1097178 Replicon chromosome
Accession NZ_CP086184
Organism Xanthomonas oryzae strain PXO280

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag LL919_RS05265 Protein ID WP_011259680.1
Coordinates 1096255..1097178 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag LL919_RS05260 Protein ID WP_011409027.1
Coordinates 1095659..1096258 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL919_RS05230 (LL919_05220) 1091386..1091760 - 375 WP_229002607.1 hypothetical protein -
LL919_RS05235 (LL919_05225) 1091741..1092031 - 291 WP_011409031.1 hypothetical protein -
LL919_RS05240 (LL919_05230) 1092530..1093563 + 1034 Protein_1000 IS630 family transposase -
LL919_RS05245 (LL919_05235) 1093699..1094497 + 799 WP_094187731.1 IS5 family transposase -
LL919_RS05250 (LL919_05240) 1094484..1094972 - 489 WP_044756654.1 BrxE family protein -
LL919_RS05255 (LL919_05245) 1095004..1095276 - 273 WP_230455482.1 FaeA/PapI family transcriptional regulator -
LL919_RS05260 (LL919_05250) 1095659..1096258 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LL919_RS05265 (LL919_05255) 1096255..1097178 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LL919_RS05270 (LL919_05260) 1097258..1097728 - 471 WP_228329666.1 helix-turn-helix domain-containing protein -
LL919_RS05275 (LL919_05265) 1098194..1098436 + 243 WP_011259679.1 hypothetical protein -
LL919_RS05280 (LL919_05270) 1098861..1099370 + 510 WP_011259678.1 hypothetical protein -
LL919_RS05285 (LL919_05275) 1099387..1099919 - 533 Protein_1009 methyltransferase domain-containing protein -
LL919_RS05290 (LL919_05280) 1099939..1101315 - 1377 Protein_1010 IS5 family transposase -
LL919_RS05295 (LL919_05285) 1101427..1101579 - 153 Protein_1011 SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T222673 WP_011259680.1 NZ_CP086184:1096255-1097178 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T222673 NZ_CP118014:1459810-1460217 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGTGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT222673 WP_011409027.1 NZ_CP086184:1095659-1096258 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT222673 NZ_CP118014:1459563-1459829 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References