222672

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4779068..4779418 Replicon chromosome
Accession NZ_CP086183
Organism Xanthomonas oryzae strain PXO341

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag LL922_RS22460 Protein ID WP_011257368.1
Coordinates 4779068..4779202 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag LL922_RS22465 Protein ID WP_011407410.1
Coordinates 4779266..4779418 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL922_RS22445 (LL922_22410) 4776085..4777029 - 945 WP_027704118.1 MBL fold metallo-hydrolase -
LL922_RS22450 (LL922_22415) 4777160..4778449 - 1290 WP_069959696.1 tryptophan--tRNA ligase -
LL922_RS22455 (LL922_22420) 4778618..4778827 - 210 WP_011407411.1 CsbD family protein -
LL922_RS22460 (LL922_22425) 4779068..4779202 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
LL922_RS22465 (LL922_22430) 4779266..4779418 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
LL922_RS22470 (LL922_22435) 4779526..4780449 - 924 WP_011407409.1 arginase -
LL922_RS22475 (LL922_22440) 4780771..4780989 + 219 Protein_4300 hypothetical protein -
LL922_RS22480 (LL922_22445) 4780981..4781436 + 456 Protein_4301 hypothetical protein -
LL922_RS22485 (LL922_22450) 4781433..4781975 + 543 Protein_4302 GTPase -
LL922_RS22490 (LL922_22455) 4782455..4783138 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T222672 WP_011257368.1 NZ_CP086183:c4779202-4779068 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T222672 NZ_CP118014:c1202456-1201992 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT222672 WP_011407410.1 NZ_CP086183:c4779418-4779266 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT222672 NZ_CP118014:c1202791-1202456 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTCTTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACACGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References