Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4240150..4240500 Replicon chromosome
Accession NZ_CP086182
Organism Xanthomonas oryzae strain PXO347

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag LL921_RS20010 Protein ID WP_011257368.1
Coordinates 4240150..4240284 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag LL921_RS20015 Protein ID WP_011407410.1
Coordinates 4240348..4240500 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL921_RS19995 (LL921_19955) 4237167..4238111 - 945 WP_027704118.1 MBL fold metallo-hydrolase -
LL921_RS20000 (LL921_19960) 4238242..4239531 - 1290 WP_069959696.1 tryptophan--tRNA ligase -
LL921_RS20005 (LL921_19965) 4239700..4239909 - 210 WP_011407411.1 CsbD family protein -
LL921_RS20010 (LL921_19970) 4240150..4240284 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
LL921_RS20015 (LL921_19975) 4240348..4240500 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
LL921_RS20020 (LL921_19980) 4240608..4241531 - 924 WP_011407409.1 arginase -
LL921_RS20025 (LL921_19985) 4241853..4242071 + 219 Protein_3823 hypothetical protein -
LL921_RS20030 (LL921_19990) 4242063..4242518 + 456 Protein_3824 hypothetical protein -
LL921_RS20035 (LL921_19995) 4242515..4243057 + 543 Protein_3825 GTPase -
LL921_RS20040 (LL921_20000) 4243537..4244220 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T222666 WP_011257368.1 NZ_CP086182:c4240284-4240150 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T222666 NZ_CP117994:c1936343-1936041 [Vibrio alginolyticus]
ATGGCTGAAATAATCTGGACTGAACCAGCGTTATCTGACCTCAACGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTAGTGCAAACGATCTTCTCCAAAGTCGAACGCCTACAAACTTTCCCAGAGTCAGGTCGTATTCCAC
CCGAGCTAGAACATCTAAGTTATCGTGAAGTTGTCGTTAATCCATGTCGTGTTTTCTATAAACAAGACGGTGACAAAGTG
TTTATTCTGTTTGTTATTCGTGCAGAGAGAGATTTGCGTAAGTTCCTGTTGAGTAAGCAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT222666 WP_011407410.1 NZ_CP086182:c4240500-4240348 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT222666 NZ_CP117994:c1936588-1936331 [Vibrio alginolyticus]
ATGAAAGTAGAACTAGTTACATCACTCAAACGTCAAGCAACTAAGATCCTCGCGGATCTCCACGATACCAAAGAGCCAGT
GTTAATTACTGAGCATGGTAAGCCATCCGCTTATCTCGTTGATGTTGATGACTACGAGTTTATGCAAAATCGTTTAGCTA
TTCTTGAGGGTATTGCACGAGGTGAGCGTGCGCTAGCTGACGGTAAAGTGATAAGCCATGATGAAGCCAAGGACAAAATG
TCAAAATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References