Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 1261069..1262588 | Replicon | chromosome |
| Accession | NZ_CP086182 | ||
| Organism | Xanthomonas oryzae strain PXO347 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | A0A0K0GMB6 |
| Locus tag | LL921_RS06090 | Protein ID | WP_011259680.1 |
| Coordinates | 1261665..1262588 (+) | Length | 308 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | A0A854CLN1 |
| Locus tag | LL921_RS06085 | Protein ID | WP_011409027.1 |
| Coordinates | 1261069..1261668 (+) | Length | 200 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LL921_RS06050 (LL921_06040) | 1256751..1257287 | - | 537 | WP_011409032.1 | lipocalin family protein | - |
| LL921_RS06060 (LL921_06050) | 1257557..1258024 | - | 468 | WP_181718264.1 | hypothetical protein | - |
| LL921_RS06065 (LL921_06055) | 1258005..1258295 | - | 291 | WP_011409031.1 | hypothetical protein | - |
| LL921_RS06070 (LL921_06060) | 1258794..1259825 | + | 1032 | WP_042465093.1 | IS630 family transposase | - |
| LL921_RS06075 (LL921_06065) | 1259807..1260382 | - | 576 | WP_011409029.1 | BrxE family protein | - |
| LL921_RS06080 (LL921_06070) | 1260414..1260704 | - | 291 | WP_228329665.1 | FaeA/PapI family transcriptional regulator | - |
| LL921_RS06085 (LL921_06075) | 1261069..1261668 | + | 600 | WP_011409027.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| LL921_RS06090 (LL921_06080) | 1261665..1262588 | + | 924 | WP_011259680.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| LL921_RS06095 (LL921_06085) | 1262668..1263138 | - | 471 | WP_228329666.1 | helix-turn-helix domain-containing protein | - |
| LL921_RS06100 (LL921_06090) | 1263604..1263846 | + | 243 | WP_011409025.1 | hypothetical protein | - |
| LL921_RS06105 (LL921_06095) | 1264298..1265263 | - | 966 | Protein_1160 | IS1595-like element ISXo5 family transposase | - |
| LL921_RS06110 (LL921_06100) | 1265358..1265846 | + | 489 | WP_069959937.1 | hypothetical protein | - |
| LL921_RS06115 (LL921_06105) | 1265863..1266395 | - | 533 | Protein_1162 | methyltransferase domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 308 a.a. Molecular weight: 34114.16 Da Isoelectric Point: 5.4588
>T222663 WP_011259680.1 NZ_CP086182:1261665-1262588 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA
Download Length: 924 bp
>T222663 NZ_CP117994:1890479-1890769 [Vibrio alginolyticus]
ATGACCTATAAACTCGACTTTAAAAAGAGCGCCCTCAAAGAGTGGAAAAAGCTTGGTTCTACTCTGCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTAGATAACCCACATGTTCCGGCTTCAAAACTATCTGGAGCTGACAACATGTATAAAATTA
AGTTGCGTCAATCGGGCTACCGTCTCGTCTACAAAGTTGAAGACGATGTCATCATTGTAACCGTCCTAGCAGTTGGAAAG
CGCGAACGTAGCGATGTTTATCGTAAAGCCATGAAAAGGTTAGATGACTGA
ATGACCTATAAACTCGACTTTAAAAAGAGCGCCCTCAAAGAGTGGAAAAAGCTTGGTTCTACTCTGCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTAGATAACCCACATGTTCCGGCTTCAAAACTATCTGGAGCTGACAACATGTATAAAATTA
AGTTGCGTCAATCGGGCTACCGTCTCGTCTACAAAGTTGAAGACGATGTCATCATTGTAACCGTCCTAGCAGTTGGAAAG
CGCGAACGTAGCGATGTTTATCGTAAAGCCATGAAAAGGTTAGATGACTGA
Antitoxin
Download Length: 200 a.a. Molecular weight: 22037.74 Da Isoelectric Point: 10.1240
>AT222663 WP_011409027.1 NZ_CP086182:1261069-1261668 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA
Download Length: 600 bp
>AT222663 NZ_CP117994:1890241-1890489 [Vibrio alginolyticus]
ATGACCACTAGAATTTTAGCCGATGTTGCTGCAAGCATTACTGAGTTAAAAGCTAACCCTATGAAAGTTGCAACTAGTGC
TTACGGCGAACCTGTTGCTGTATTAAACCGAAATGAACCAGCATTTTATTGCGTACCTGCCGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTCGCTATCGCTAAAGAGCGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA
ATGACCACTAGAATTTTAGCCGATGTTGCTGCAAGCATTACTGAGTTAAAAGCTAACCCTATGAAAGTTGCAACTAGTGC
TTACGGCGAACCTGTTGCTGTATTAAACCGAAATGAACCAGCATTTTATTGCGTACCTGCCGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTCGCTATCGCTAAAGAGCGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0K0GMB6 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A854CLN1 |