Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1261069..1262588 Replicon chromosome
Accession NZ_CP086182
Organism Xanthomonas oryzae strain PXO347

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag LL921_RS06090 Protein ID WP_011259680.1
Coordinates 1261665..1262588 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag LL921_RS06085 Protein ID WP_011409027.1
Coordinates 1261069..1261668 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL921_RS06050 (LL921_06040) 1256751..1257287 - 537 WP_011409032.1 lipocalin family protein -
LL921_RS06060 (LL921_06050) 1257557..1258024 - 468 WP_181718264.1 hypothetical protein -
LL921_RS06065 (LL921_06055) 1258005..1258295 - 291 WP_011409031.1 hypothetical protein -
LL921_RS06070 (LL921_06060) 1258794..1259825 + 1032 WP_042465093.1 IS630 family transposase -
LL921_RS06075 (LL921_06065) 1259807..1260382 - 576 WP_011409029.1 BrxE family protein -
LL921_RS06080 (LL921_06070) 1260414..1260704 - 291 WP_228329665.1 FaeA/PapI family transcriptional regulator -
LL921_RS06085 (LL921_06075) 1261069..1261668 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LL921_RS06090 (LL921_06080) 1261665..1262588 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LL921_RS06095 (LL921_06085) 1262668..1263138 - 471 WP_228329666.1 helix-turn-helix domain-containing protein -
LL921_RS06100 (LL921_06090) 1263604..1263846 + 243 WP_011409025.1 hypothetical protein -
LL921_RS06105 (LL921_06095) 1264298..1265263 - 966 Protein_1160 IS1595-like element ISXo5 family transposase -
LL921_RS06110 (LL921_06100) 1265358..1265846 + 489 WP_069959937.1 hypothetical protein -
LL921_RS06115 (LL921_06105) 1265863..1266395 - 533 Protein_1162 methyltransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T222663 WP_011259680.1 NZ_CP086182:1261665-1262588 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T222663 NZ_CP117994:1890479-1890769 [Vibrio alginolyticus]
ATGACCTATAAACTCGACTTTAAAAAGAGCGCCCTCAAAGAGTGGAAAAAGCTTGGTTCTACTCTGCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTAGATAACCCACATGTTCCGGCTTCAAAACTATCTGGAGCTGACAACATGTATAAAATTA
AGTTGCGTCAATCGGGCTACCGTCTCGTCTACAAAGTTGAAGACGATGTCATCATTGTAACCGTCCTAGCAGTTGGAAAG
CGCGAACGTAGCGATGTTTATCGTAAAGCCATGAAAAGGTTAGATGACTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT222663 WP_011409027.1 NZ_CP086182:1261069-1261668 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT222663 NZ_CP117994:1890241-1890489 [Vibrio alginolyticus]
ATGACCACTAGAATTTTAGCCGATGTTGCTGCAAGCATTACTGAGTTAAAAGCTAACCCTATGAAAGTTGCAACTAGTGC
TTACGGCGAACCTGTTGCTGTATTAAACCGAAATGAACCAGCATTTTATTGCGTACCTGCCGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTCGCTATCGCTAAAGAGCGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References