Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3314145..3315664 Replicon chromosome
Accession NZ_CP086181
Organism Xanthomonas oryzae strain PXO349

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag LL917_RS15450 Protein ID WP_011259680.1
Coordinates 3314145..3315068 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag LL917_RS15455 Protein ID WP_011409027.1
Coordinates 3315065..3315664 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL917_RS15425 (LL917_15425) 3310338..3310870 + 533 Protein_2947 methyltransferase domain-containing protein -
LL917_RS15430 (LL917_15430) 3310887..3311375 - 489 WP_069959937.1 hypothetical protein -
LL917_RS15435 (LL917_15435) 3311470..3312435 + 966 Protein_2949 IS1595-like element ISXo5 family transposase -
LL917_RS15440 (LL917_15440) 3312887..3313129 - 243 WP_011409025.1 hypothetical protein -
LL917_RS15445 (LL917_15445) 3313595..3314065 + 471 WP_228329666.1 helix-turn-helix domain-containing protein -
LL917_RS15450 (LL917_15450) 3314145..3315068 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LL917_RS15455 (LL917_15455) 3315065..3315664 - 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LL917_RS15460 (LL917_15460) 3316029..3316319 + 291 WP_228329665.1 FaeA/PapI family transcriptional regulator -
LL917_RS15465 (LL917_15465) 3316351..3316926 + 576 WP_011409029.1 BrxE family protein -
LL917_RS15470 (LL917_15470) 3316908..3317939 - 1032 WP_042465093.1 IS630 family transposase -
LL917_RS15475 (LL917_15475) 3318438..3318728 + 291 WP_011409031.1 hypothetical protein -
LL917_RS15480 (LL917_15480) 3318709..3319176 + 468 WP_181718264.1 hypothetical protein -
LL917_RS15490 (LL917_15490) 3319446..3319982 + 537 WP_011409032.1 lipocalin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T222661 WP_011259680.1 NZ_CP086181:c3315068-3314145 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T222661 NZ_CP117993:4386463-4386783 [Enterobacter hormaechei]
ATGAAAACTCAACCTGCAACAACTCCGCAGGCGGCGAAGCCATGTCTGTCGCCCCTGGCTGTCTGGCAAATGTTACTGAC
AAGCCTGCTAGACCAGCACTATGGTCTCACGCTAAACGACACGCCGTTCAGTGATGAAACTGTTATTCAGAAACACATTG
AGGCAGGTATTACCTTGGCCGATGCCGTAAACTTTCTGGTTGAACGCTATGAACTAGTTCGTATTGACCAAAAAGGCTTC
TCTGTGCAAGATCAAGAACCTTGGTTAACCTCTATGGATGTTCACCGAGCACGATTTAAACTCAACGTGGAACGTTTATA
A

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT222661 WP_011409027.1 NZ_CP086181:c3315664-3315065 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT222661 NZ_CP117993:4386116-4386442 [Enterobacter hormaechei]
ATGTCATTAATACCAGCCCATGAATGGGGACTACAAAGAGAAATTGTTCCACGGTTTGGTGCCAGATTAGTTCAGGAGGG
CAACCGGCTGCATTATCTGGCTGACAGGGCTAATTTGATGGGCAATTTCAGCGATACGGAATGCTTCAAATTGAATGACG
CATTTCCACACTTTATCAGTCAGATGGAATCGATGCTGACCACTGGTGAACTAATCCCCTGTCACCATCACTGTGTCACT
CTCTACCACAACGGTTTTACCTGCGAAGCCGACACCCTTGGCAGTTGCGGCTACGTGTACATCGCGGTTTATCCCACTCA
ACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References