222659

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1007284..1008029 Replicon chromosome
Accession NZ_CP086181
Organism Xanthomonas oryzae strain PXO349

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag LL917_RS04870 Protein ID WP_199285672.1
Coordinates 1007700..1008029 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag LL917_RS04865 Protein ID WP_011407754.1
Coordinates 1007284..1007703 (-) Length 140 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL917_RS04845 (LL917_04850) 1003573..1003899 - 327 Protein_914 hypothetical protein -
LL917_RS04850 (LL917_04855) 1004201..1005436 + 1236 WP_011257570.1 ISL3-like element ISXoo13 family transposase -
LL917_RS04855 (LL917_04860) 1005474..1006154 - 681 WP_011257926.1 phosphate phosphatase -
LL917_RS04865 (LL917_04870) 1007284..1007703 - 420 WP_011407754.1 macro domain-containing protein Antitoxin
LL917_RS04870 (LL917_04875) 1007700..1008029 - 330 WP_199285672.1 DUF4433 domain-containing protein Toxin
LL917_RS04875 (LL917_04880) 1008132..1009451 + 1320 WP_155296575.1 IS701-like element ISXo15 family transposase -
LL917_RS04880 (LL917_04885) 1009495..1009830 - 336 WP_011407757.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
LL917_RS04885 (LL917_04890) 1010162..1011088 - 927 WP_011257932.1 Grx4 family monothiol glutaredoxin -
LL917_RS04890 (LL917_04895) 1011134..1011925 + 792 WP_011407758.1 polysaccharide deacetylase family protein -
LL917_RS04900 (LL917_04905) 1012227..1012898 - 672 WP_011407759.1 class I SAM-dependent methyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 1004201..1009451 5250


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-108)

Antitoxin

(18-130)


Sequences


Toxin        


Download         Length: 110 a.a.        Molecular weight: 13145.86 Da        Isoelectric Point: 7.1160

>T222659 WP_199285672.1 NZ_CP086181:c1008029-1007700 [Xanthomonas oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Download         Length: 330 bp

>T222659 NZ_CP117993:3366876-3367094 [Enterobacter hormaechei]
ATGTCTGATAAACCATTAACAAAAGTCGATTATTTGATGCGCCTGCGACGCTGCCAGTCAATTGACACCCTTGAACGAGT
TATTGAGAAAAATAAATACGAGCTGTCTGATAATGAACTGGCGGTATTTTATTCAGCTGCCGACCATCGTCTTGCTGAGC
TGACCATGAATAAACTGTATGACAAGATCCCCTCTTCGGTGTGGAAATTTGTTCGTTAA

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15607.02 Da        Isoelectric Point: 6.4733

>AT222659 WP_011407754.1 NZ_CP086181:c1007703-1007284 [Xanthomonas oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Download         Length: 420 bp

>AT222659 NZ_CP117993:3366474-3366848 [Enterobacter hormaechei]
ATGGACGAGTACTCGCCAAAAAGGCATGATATCGCGCAGTTGAAATTTCTCTGCGAATCCTTGTACCATGACTGCCTTGC
CAATCTTGAAGAAAGTAACCATGGCTGGGTGAACGATCCAACGTCTGCTATCAATTTACAGCTCAACGAGCTGATCGAGC
ATATCGCCACCTTCGCACTTAATTATAAAATTAAGTACAATGAAGATAATAAGTTGATAGAGCAAATTGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTACGGCATTAACGCACAGGATTTGCAGAAATGGCGTAAATCAGGAAACCGTCT
ATTTCGCTGCTTCACTAATGTCAGCAGAGCTAATCCGGTTAGTCTTTCCTGTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References