Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 344440..344790 Replicon chromosome
Accession NZ_CP086181
Organism Xanthomonas oryzae strain PXO349

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag LL917_RS01635 Protein ID WP_011257368.1
Coordinates 344656..344790 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag LL917_RS01630 Protein ID WP_011407410.1
Coordinates 344440..344592 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL917_RS01605 (LL917_01600) 340720..341403 - 684 WP_011257363.1 dTMP kinase -
LL917_RS01610 (LL917_01605) 341883..342425 - 543 Protein_305 GTPase -
LL917_RS01615 (LL917_01610) 342422..342877 - 456 Protein_306 hypothetical protein -
LL917_RS01620 (LL917_01615) 342869..343087 - 219 Protein_307 hypothetical protein -
LL917_RS01625 (LL917_01620) 343409..344332 + 924 WP_011407409.1 arginase -
LL917_RS01630 (LL917_01625) 344440..344592 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
LL917_RS01635 (LL917_01630) 344656..344790 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
LL917_RS01640 (LL917_01635) 345031..345240 + 210 WP_011407411.1 CsbD family protein -
LL917_RS01645 (LL917_01640) 345409..346698 + 1290 WP_069959696.1 tryptophan--tRNA ligase -
LL917_RS01650 (LL917_01645) 346829..347773 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T222658 WP_011257368.1 NZ_CP086181:344656-344790 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T222658 NZ_CP117993:c2740003-2739482 [Enterobacter hormaechei]
GTGGCAAATCTCACGATCGAAATGTTATCAGAGGGAACCGATTACGATTTCGGCGATTTCGATTGTGGTGAACCCTCGCT
CAATGCCTTCCTTACCGATCACCTGGTGCGTCAGCATGGCGGGCGTATTTTACGCGGCTACCTGCTTAAAGAACGCGACC
ATCCGCGTATCCTGGGCTATTACACCCTTTCGGGAAGTTGCTTTGAAAAAGCGATGCTTCCTTCAAAGACTCAGCAGCGC
CGCATCCCATACAGCAACGTCCCCAGCGTGACGCTGGGACGTCTGGCTGTCCATAAAGAACTACAGGGAAACGAGTGGGG
AACAACGCTTGTCACACACGCTATGCGCGTGGTTTATCTGGCGTCGCAGGCTGTTGGCGTCCACGGAATTTTTGTGGATG
CGCTTAACGAACGGGCCAAACGATTTTATCTGAAGCTGGGGTTTATCCCGCTGGCAGGTGAAAACAGCAGTTCGCTGTTC
TTCCCCACGCAATCTATAGAACGACTGTTTGAGCAGGCGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT222658 WP_011407410.1 NZ_CP086181:344440-344592 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT222658 NZ_CP117993:c2740279-2740010 [Enterobacter hormaechei]
ATGCCAGCACTCAAAAAACAGCGTATCGATCTTCGCCTGTCGGACGAAGACAAAACAATGATTGAAGAAGCGGCAGCGAT
GACCAACCAAACGATCACCCAGTTTATGGTGAACAGTGCGTCAGAGCGTGCTGCCGAAGTCATCGAACAGCATCGGCGTC
TCGTATTAAACGAAGCCTCATGGAATGCCGTTATGGATGCCATCGACAATCCACCAGAGCCAAATGAACGCCTGAAGCGA
GCGGCGAAACGTCTTCGAAACATGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References